6852-78-4

Usage

Uses

Used in Pharmaceutical, Agrochemical, and Specialty Chemical Industries:
(R)-(-)-1,2-Diaminopropane is used as a building block for the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals. Its chiral nature makes it a valuable component in the development of enantiomerically pure compounds, which are essential in the pharmaceutical industry for their targeted therapeutic effects and reduced side effects.
Used in Manufacturing of Polyurethane Foams:
(R)-(-)-1,2-Diaminopropane is used as a curing agent in the production of polyurethane foams. Its reactivity contributes to the formation of the desired foam structure, enhancing the material's properties such as flexibility, durability, and insulation capabilities.
Used in Epoxy Resin and Coating Industries:
In the epoxy resin and coating industries, (R)-(-)-1,2-Diaminopropane serves as a curing agent. Its role in the curing process improves the mechanical strength, chemical resistance, and adhesion properties of the final epoxy products, making them suitable for a wide range of applications, including automotive, aerospace, and construction sectors.
Used in Corrosion Inhibition:
(R)-(-)-1,2-Diaminopropane is also utilized in the manufacturing of corrosion inhibitors. Its ability to form complexes with metal surfaces helps protect them from corrosion, extending the lifespan of materials and structures in various industrial applications.
Safety Considerations:

Upstream product

• 78-90-0 1,2-diaminopropan 
• 122833-55-0 (R)-2-Ethoxy-4-methyl-4,5-dihydro-1H-imidazole 
• 19777-66-3 (R)-propane-1,2-diamine dihydrochloride 

Downstream Products

• 122920-65-4 (R)-1.2-bis-benzamino-propane 
• 19237-25-3 bis-(salicylidene)-D(-)-propylenediamine 
• 72098-54-5 N¹,N²-dibenzylidene-1,2-propanediamine 
• 75040-70-9 N¹,N²-dibenzyl-1,2-propanediamine 
• 72098-53-4 N¹-benzyl-1,2-propanediamine 
• 75730-12-0 (R)-1,2-bis<(diphenylphosphino)amino>propane 
• 13408-73-6 [tris(1,2-diaminoethane)cobalt(III)] chloride 
• 15276-13-8 d-{Cren3}(3+) 
• 1334305-20-2 (R)-2-amino-1-(2-hydroxybenzamide)propane 

Relevant academic research and scientific papers

Polymethacrylic zinc porphyrin: A new approach to chiral recognition

A methacrylic homopolymer bearing in the side-chain achiral zinc tetraarylporphyrin moieties, has been studied as macromolecular chromophoric host to determine the absolute configuration of α,ω-diamines. The polymeric material resulted able to bind the ch

β-PNA: Peptide nucleic acid (PNA) with a chiral center at the β-position of the PNA backbone

Peptide nucleic acid (PNA) monomers with a methyl group at the β-position have been synthesized. The modified monomers were incorporated into PNA oligomers using Fmoc chemistry for solid-phase synthesis. Thermal denaturation and circular dichroism (CD) studies have shown that PNA containing the S-form monomers was well suited to form a hybrid duplex with DNA, whose stability was comparable to that of unmodified PNA-DNA duplex, whereas PNA containing the R-form monomers was not.

SYNTHESIS OF CHIRAL 1,2-DIAMINES

(1'S,5R,S)-(1'-phenyleth-1'-yl)-5-iodomethyl-imidazolines 4a, b have been synthesised and easily resolved by silica gel chromatography.The correlation between the configuration and the 1H-NMR chemical shifts allows to assign the configuration at the C-5 of these intermediates.Each pure diastereomer has been converted to R(-)- and to S(+)-1,2-propyldiamine, respectively.