6852-94-4

Basic information

• Product Name: Pent-4-enamide
• Synonyms: Pent-4-enamide
• CAS NO: 6852-94-4
• Molecular Formula: C₅H₉NO
• Molecular Weight: 99.13106
• Mol File: 6852-94-4.mol

Chemical Properties

• Boiling Point: 230.4°C at 760 mmHg
• Flash Point: 93.1°C
• Appearance: /
• Density: 0.926g/cm³
• Vapor Pressure: 0.0661mmHg at 25°C
• Refractive Index: 1.445
• CAS DataBase Reference: Pent-4-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: Pent-4-enamide(6852-94-4)
• EPA Substance Registry System: Pent-4-enamide(6852-94-4)

Safety Data

• Hazardous Substances Data: 6852-94-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H9NO/c1-2-3-4-5(6)7/h2H,1,3-4H2,(H2,6,7)

Upstream product

• 263758-55-0 C₅₁H₅₉N₃O₅ 
• 263758-54-9 C₅₀H₅₅N₃O₅ 
• 263758-52-7 C₅₄H₅₈N₄O₅ 
• 17342-08-4 (S)-Pyroglutaminol 
• 872164-42-6 N-(phenylthio)pent-4-enamide 

Downstream Products

• 5831-75-4 5-(iodomethyl)-2-pyrrolidinone 
• 22537-07-1 4-pentenyl-1-amine 
• 861882-24-8 N-(pent-4-enyl)-4-(trifluoromethyl)benzamide 
• 113261-21-5 N-(pent-4-enyl)-4-methoxybenzamide 
• 60216-38-8 5-(acetoxymethyl)-2-pyrrolidinone 
• 154148-69-3 5-(aminomethyl)-2-pyrrolidinone 
• 115307-31-8 1-<2-(phenylsulfonyl)ethyl>-5-(iodomethyl)-2-pyrrolidinone 
• 115307-30-7 1-<(Z)-2-(phenylsulfonyl)ethenyl>-5-(iodomethyl)-2-pyrrolidinone 
• 115307-29-4 1-<(E)-2-(phenylsulphonyl)ethenyl>-5-(iodomethyl)-2-pyrrolidinone 
• 62400-75-3 pyroglutamol 
• 628-94-4 adipamide 
• 90205-02-0 7-oxooctanoic amide 
• 105-60-2 caprolactam 
• 89464-19-7 1,3,4,5-tetrahydroazepin-2-one 

Relevant articles and documents

Copper(I) mediated cross-coupling of amino acid derived organozinc reagents with acid chlorides

This paper describes the development of a straightforward experimental protocol for copper-mediated cross-coupling of amino acid derived β-amido-alkylzinc iodides 1 and 3 with a range of acid chlorides. The present method uses CuCN·2LiCl as the copper source and for organozinc reagent 1 the methodology appears to be limited to reaction with more stable acid chlorides, providing the desired products in moderate yields. When applied to organozinc reagent 3, however, the protocol is more general and provides the products in good yields in all but one of the cases tested. The Royal Society of Chemistry 2006.

First examples of intramolecular addition of primary amidyl radicals to olefins

The first examples of intramolecular addition of primary amidyl radicals to olefins are described. Amidyl radicals were generated from N-(phenylthio)amides in refluxing benzene using a catalytic amount of 2,2′- azobis(isobutyronitrile) (5 mol%) and tributyltin hydride (sim;2.2 equiv.). The resulting yields of cyclic products ranged from 63% to 85%.

CHEMICAL CONSTRUCTS

The invention provides a chemical construct for use in solid phase synthesis comprising a solid support Q having linked thereto via a connecting group Y a substrate R; the connecting group Y having first and second cleavage sites which are orthogonally and selectively cleavable; the second cleavage site being selectively cleavable to release the substrate; and the first cleavage site being located at a position between the second cleavage site and the solid support and being selectively cleavable to release a fragment Fr comprising the substrate and at least a portion of the connecting group Y; characterised in that cleavage at the first cleavage site forms or introduces on the chemical fragment Fr at the first cleavage site a moiety comprising a sensitising group G (such as an amino group) which sensitises the chemical fragment Fr to instrumental, e.g. mass spectroscopic, analysis. Also provided are methods of analysis employing the constructs, as well as intermediate constructs.