685895-47-0

Upstream product

• 685895-46-9 acetic acid acetoxy-(2,4-dimethoxy-3-methyl-5-nitro-phenyl)-methyl ester 
• 7149-92-0 2,4-dimethoxy-3-methylbenzaldehyde 

Downstream Products

• 685895-45-8 2-bromo-4,6-dihydroxy-5-methylbenzaldehyde 
• 685895-62-9 2,4-dihydroxy-6-(3-methoxyprop-1-yn-1-yl)-3-methylbenzaldehyde 
• 859507-78-1 2,4-dihydroxy-3-methyl-6-non-1-ynyl-benzaldehyde 
• 685895-68-5 2-benzyl-3-heptyl-7-hydroxy-7-methyl-2H-isoquinoline-6,8-dione 
• 685895-63-0 cyclohexanecarboxylic acid [3-(2-formyl-3,5-dihydroxy-4-methyl-phenyl)-prop-2-ynyl]-amide 
• 685895-58-3 3-heptyl-7-(2-iodo-phenyl)-7-methyl-isochromene-6,8-dione 
• 685895-48-1 6-bromo-2,4-dimethoxy-3-methylbenzaldehyde 

Relevant academic research and scientific papers

Synthesis of azaphilones and related molecules by employing cycloisomerization of o-alkynylbenzaldehydes

Right to the core: Gold(III)-catalyzed cycloisomerization of o-alkynylbenzaldehydes to 2-benzopyrylium salts and subsequent in situ oxidation have been employed to prepare the core structure of azaphilone natural products, such as the sphingosine kinase inhibitor S-15183 (see scheme, DCE = 1,2-dichloroethane, TFA = trifluoroacetic acid)), and several unnatural azaphilones.