68597-45-5

Upstream product

• 22256-43-5 2-methoxy-3-methylbenzoyl chloride 
• 999-75-7 ethylzinc iodide 
• 77-78-1 dimethyl sulfate 
• 26507-91-5 2-methoxy-3-methylbenzoic acid 
• 83-40-9 3-methylsalicylic acid 
• 90609-90-8 2-methoxy-3-methyl-benzoic acid amide 
• 941-74-2 1-(5-chloro-2-hydroxy-3-methylphenyl)-1-propanone 
• 1570-64-5 2-methyl-4-chlorophenol 
• 107076-03-9 1-(5-chloro-2-methoxy-3-methylphenyl)-1-propanone 

Downstream Products

• 105207-16-7 3-(2-methoxy-3-methyl-phenyl)-2-methyl-3-oxo-propionaldehyde 
• 190004-76-3 1-(2-methoxy-3-methylphenyl)-2-methyl-2-propen-1-one 

Relevant academic research and scientific papers

Synthesis of metabolites of the cerebroprotecting agent 7-hydroxy-1- [[[4-(3-methoxyphenyl)-1-piperazinyl]acetyl]amino]-2,2,4,6-tetramethylindan (OPC-14117)

A hydroxylated metabolite (5a) of 7-hydroxy-1-[[[4-(3-methoxyphenyl)-1- piperazinyl]acetyl]amino]-2,2,4,6-tetramethylindan (OPC-14117), which is a novel cerebroprotective agent with central nervous system-stimulating activity, was synthesized by use of a model cytochrome P-450 system. In order to confirm the structure of this compound it was prepared by another route. The structures of several metabolites (5a, 7 and 8) were identified by means of comparisons with the synthetic compounds.