6860-79-3

Upstream product

• 24239-67-6 4-(benzyloxy)-1-methyl-2-nitrobenzene 
• 95-92-1 oxalic acid diethyl ester 
• 112089-51-7 diethyl <4-(benzyloxy)-2-nitrophenyl>malonate 

Downstream Products

• 413577-21-6 2-(4-benzyloxy-2-nitrophenyl)ethanol 
• 413577-25-0 2-(2-amino-4-hydroxyphenyl)ethyl bromide 
• 413577-24-9 2-(2-amino-4-hydroxyphenyl)-ethyl chloride 
• 413577-26-1 2-(2-amino-4-benzyloxyphenyl)ethyl chloride 
• 413577-23-8 2-(4-benzyloxy-2-nitrophenyl)ethyl bromide 
• 413577-22-7 2-(4-benzyloxy-2-nitrophenyl)ethyl chloride 
• 458526-04-0 C₁₇H₁₇NO₅ 
• 413577-00-1 4-(2-chloroethyl)-3-[[5-(4-bis-(2-chloroethyl)amino)benzamido]indole-2-carboxamido]phenol 
• 413576-98-4 N-(2-(2-bromoethyl)-4-hydroxyphenyl)-1-methyl-4-(1-methyl-4-butanamido pyrrole-2-carboxamido)pyrrole-2-carboxamide 
• 413576-92-8 4-(2-chloroethyl)-3-[5-(5-benzofuran-2-carboxamido)indole-2-carboxamido]phenol 
• 413578-29-7 benzyl 4-(2-chloroethyl)-3-[5,6,7-trimethoxyindole-2-carboxamido]phenyl ether 

Relevant academic research and scientific papers

Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

1 H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of -disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: Design, synthesis, DNA binding, and anticancer properties

The synthesis, DNA binding properties, and in vitro and in vivo anticancer activity of fifteen achiral seco-cyclopropylindoline (or achiral seco-CI) analogs (5a-o) of CC-1065 and the duocarmycins are described. The achiral seco-CI analogs contain a 4-hydr

Compositions and methods of the use thereof achiral analogues of CC-1065 and the duocarmycins

The present invention relates to novel achiral seco-analogues of DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II, III, IV and V: wherein X is a good leaving group, such as a chlori

Compositions and methods of the use thereof achiral analogues of CC-1065 and the duocarmycins

The present invention relates to novel achiral seco-analogues of the DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II III, IV and V: wherein X is a good leaving group, such as a chl