68634-02-6

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 1-oxo-2,3-dihydro-1H-indene-5-carboxylate is utilized as a key intermediate for the synthesis of new drugs, leveraging its potential biological activity and pharmacological properties to contribute to the development of innovative medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, Methyl 1-oxo-2,3-dihydro-1H-indene-5-carboxylate serves as a crucial building block in the creation of various agrochemical products, potentially enhancing crop protection and yield through its integration into chemical formulations.
Used in Fragrance Industry:
Methyl 1-oxo-2,3-dihydro-1H-indene-5-carboxylate is employed as a component in the fragrance industry, where its unique chemical structure contributes to the development of novel scents and perfumes.
Used in Organic Synthesis:
As a versatile intermediate in organic chemistry, Methyl 1-oxo-2,3-dihydro-1H-indene-5-carboxylate is applied across various scientific and technological fields, facilitating the synthesis of a wide array of chemical compounds for diverse applications.

Upstream product

• 67-56-1 methanol 
• 3470-45-9 1-oxo-2,3-dihydro-1H-indene-5-carboxylic acid 
• 496-11-7 INDANE 
• 91880-84-1 1-oxo-indan-5-carboxylic acid amide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 201230-82-2 carbon monoxide 
• 34598-49-7 5-Bromo-1-indanone 
• 65898-38-6 indan-5-carboxylic acid 
• 4228-10-8 1-indan-5-yl-ethanone 
• 86031-43-8 methyl 5-indanecarboxylate 
• 186581-53-3 diazomethane 
• 105469-25-8 1,4,7,7aα-tetrahydro-1-oxo-4α,7α-methano-3aH-indene-(3aR)-3aα-carboxylic acid 
• 15497-40-2 2,3-dihydroindene-5-carbonyl chloride 

Downstream Products

• 168560-79-0 1-aminoindan-1,5-dicarboxylic acid 
• 3470-45-9 1-oxo-2,3-dihydro-1H-indene-5-carboxylic acid 
• 903557-36-8 methyl (1S)-1-aminoindane-5-carboxylate 
• 1415502-43-0 methyl (1S)-1-{[(1S)-1-(4-methoxyphenyl)ethyl]amino}indane-5-carboxylate 
• 1260116-74-2 methyl 1-(2-benzoylhydrazono)-2,3-dihydro-1H-indene-5-carboxylate 

Relevant academic research and scientific papers

Rational Design, Synthesis, and Pharmacological Characterization of Novel Ghrelin Receptor Inverse Agonists as Potential Treatment against Obesity-Related Metabolic Diseases

A new chemotype of ghrelin inverse agonists was discovered through chimeric design based on molecular scaffolds known as growth-hormone secretagogue receptor (GHSR) modulators but with divergent pharmacodynamic and pharmacokinetic properties. The structur

2-SPIRO-5- AND 6-HYDROXAMIC ACID INDANES AS HDAC INHIBITORS

The present invention is directed to inhibitors of histone deacetylases (HDACs) such as HDAC6, and their use in the treatment of diseases such as cell proliferative diseases (e.g., cancer), neurological (e.g., neurodegenerative disease or neurodevelopmental disease), inflammatory or autoimmune disease, infection, metabolic disease, hematologic disease, or cardiovascular disease.

AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS

The invention provides certain amino-pyridine-containing compounds of the Formula (I) (I) or pharmaceutically acceptable salts thereof, wherein R3, R4, R5, R6, and the subscript n are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.

HETEROTETRACYCLIC COMPOUNDS AS TPO MIMETICS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TPO activity, particularly diseases or disorders that involve thrombocytopenia.

Raf inhibitor compounds and methods of use thereof

Compounds of Formula I are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Syntheses of compounds active toward glutamate receptors: I. New preparative synthesis of aminoindandicarboxylic acid (AIDA)

A preparative procedure has been developed for the synhtesis of 1-aminoindan-1,5-dicarboxylic acid which is a new group I metabotropic glutamate receptor antagonist.