686744-85-4Relevant academic research and scientific papers
A Bulky Three-Hindered Quadrant Bisphosphine Ligand: Synthesis and Application in Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes
Sawatsugawa, Yuuki,Tamura, Ken,Sano, Natsuhiro,Imamoto, Tsuneo
supporting information, p. 8874 - 8878 (2019/11/03)
A bulky three-hindered quadrant bisphosphine ligand, di-1-adamantylphosphino(tert-butylmethylphosphino)methane, named BulkyP*, has been synthesized via a convergent short pathway with chromatography-free procedures. The ligand is a crystalline solid and can be readily handled in air. Its rhodium(I) complex exhibits very high enantioselectivities and catalytic activities in the asymmetric hydrogenation of functionalized alkenes.
A Versatile Chemo-Enzymatic Route to Enantiomerically Pure β-Branched α-Amino Acids
Roff, Geoffrey J.,Lloyd, Richard C.,Turner, Nicholas J.
, p. 4098 - 4099 (2007/10/03)
A series of diastereoisomers of β-methyl-β-phenylalanine analogues 1a?f have been prepared in enantiomerically pure form using a combination of chemo- and biocatalysis. Starting from l-threonine methyl ester 2, a range of β,β-disubstituted didehydroamino
Catalytic asymmetric hydrogenation of α-(acetamido)acrylates using TRAP trans-chelating chiral bisphosphine ligands: Remarkable effects of ligand P-substituent and hydrogen pressure on enantioselectivity
Kuwano,Sawamura,Ito
, p. 2571 - 2578 (2007/10/03)
The catalytic asymmetric hydrogenation of α-(acetamido)acrylates was carded out with the rhodium complexes prepared from [Rh(cod)2]BF4 and trans-chelating chiral bisphosphine ligands, (S,S)-2,2'-bis[(R)-1-(dialkylphosphino)ethyl]-1,1
