6878-08-6Relevant articles and documents
Rat small intestine muscle relaxation alkaloids from Orixa japonica leaves
Funayama, Shinji,Tanaka, Rioko,Kumekawa, Yasuhiro,Noshita, Toshiro,Mori, Tetsuya,Kashiwagura, Tadashi,Murata, Kiyoshi
, p. 100 - 102 (2001)
Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle rel
Short step synthesis of natural 2-arylquinolones based on iridium-catalyzed three-component coupling quinoline synthesis
Nakajima, Takayuki,Inada, Takashi,Shimizu, Isao
, p. 497 - 504 (2008/02/03)
Eduline (la), graveoline (1b), and 6-methoxy-2-(4-methoxyphenyl)-1-methylquinolone (1c) were synthesized by iridium-catalyzed three-component coupling reaction. Reaction of an aniline, an aromatic aldehyde, and acetaldehyde gave the corresponding substitu
The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 9. Synthesis of 2-Arylquinoline Alkaloids
Coppola, Gary M.
, p. 727 - 731 (2007/10/02)
A one-step synthesis of N-methyl-2-aryl-4-quinolone alkaloids is described.These compounds are readily prepared from the reaction of an N-methylisatoic anhydride with the lithium enolate of an acetophenone.By this method, the reaction of N-methylisatoic a
