690254-87-6Relevant articles and documents
Syntheses of the antibiotic alkaloids renierone, mimocin, renierol, renierol acetate, renierol propionate, and 7-methoxy-1,6-dimethylisoquinoline-5, 8-dione
Kuwabara, Nagako,Hayashi, Hiroyuki,Hiramatsu, Noriko,Choshi, Tominari,Kumemura, Teppei,Nobuhiro, Junko,Hibino, Satoshi
, p. 2943 - 2952 (2007/10/03)
The total synthesis of renierone, mimocin, renierol, renierol acetate, renierol propionate, and 7-methoxy-1,6-dimethylisoquinoline-5,8-dione was successfully achieved by the regioselective oxidation of 5-oxygenated isoquinoline. The synthetic method of the 5-oxygenated isoquinoline is based on the thermal electrocyclic reaction of 1-azahexatriene system involving the benzene 1,2-bond.