258289-45-1

Upstream product

• 258289-44-0 2-benzyloxy-4-[α-(tert-butyldimethylsilyloxy)acetyl]-3-ethenyl-6-methoxytoluene 
• 54700-36-6 2-hydroxy-4-methoxy-3-methylbenzaldehyde 
• 7149-92-0 2,4-dimethoxy-3-methylbenzaldehyde 
• 105103-95-5 2-(benzyloxy)-4-methoxy-3-methylphenol 
• 258289-39-3 3-benzyloxy-2-hydroxy-5-methoxy-4-methylbenzaldehyde 
• 258289-41-7 3-benzyloxy-2-ethenyl-5-methoxy-4-methylbenzaldehyde 
• 258289-42-8 1-(3-benzyloxy-2-ethenyl-5-methoxy-4-methylphenyl)ethane-1,2-diol 

Downstream Products

• 258289-46-2 1-(tert-butyldimethylsilyloxymethyl)-5-benzyloxy-7-methoxy-6-methylisoquinoline 
• 73777-65-8 (5,8-dihydro-7-methoxy-6-methyl-5,8-dioxo-1-isoquinolinyl)methyl (2Z)-2-methyl-2-butenoate 
• 258289-51-9 (5-hydroxy-7-methoxy-6-methylisoquinol-1-yl)methyl acetate 
• 258289-47-3 5-benzyloxy-1-hydroxymethyl-7-methoxy-6-methylisoquinoline 
• 258289-49-5 (5-benzyloxy-7-methoxy-6-methylisoquinol-1-yl)methyl acetate 
• 258289-50-8 (5-benzyloxy-7-methoxy-6-methylisoquinol-1-yl)methyl propionate 
• 690254-85-4 5-benzyloxy-1,6-dimethyl-7-methoxyisoquinoline 
• 690254-86-5 1-azidomethyl-5-benzyloxy-7-methoxy-6-methylisoquinoline 
• 690254-83-2 (5-benzyloxy-7-methoxy-6-methylisoquinol-1-yl)methyl angelate 
• 690254-87-6 5-benzyloxy-7-methoxy-6-methyl-1-(pyruvoylaminomethyl)isoquinoline 
• 690254-84-3 5-benzyloxy-7-methoxy-6-methyl-1-(4-toluene-sulfonyloxymethyl)isoquinoline 

Relevant academic research and scientific papers

Syntheses of the antibiotic alkaloids renierone, mimocin, renierol, renierol acetate, renierol propionate, and 7-methoxy-1,6-dimethylisoquinoline-5, 8-dione

The total synthesis of renierone, mimocin, renierol, renierol acetate, renierol propionate, and 7-methoxy-1,6-dimethylisoquinoline-5,8-dione was successfully achieved by the regioselective oxidation of 5-oxygenated isoquinoline. The synthetic method of the 5-oxygenated isoquinoline is based on the thermal electrocyclic reaction of 1-azahexatriene system involving the benzene 1,2-bond.