69056-25-3

Usage

Also Known As

Phenylacetylsalicylic acid

Chemical Class

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Properties

Analgesic: Relieves pain.
Anti-inflammatory: Reduces inflammation.
Antipyretic: Reduces fever.

Mechanism of Action

Inhibits the production of prostaglandins, which are responsible for pain and inflammation.

Therapeutic Uses

Treatment of pain
Treatment of fever
Treatment of inflammation

Adverse Effects

Gastrointestinal bleeding
Kidney damage

Caution

Prolonged use or high doses may lead to adverse effects.

Recommendation

Use under the guidance of a healthcare professional.

InChI:InChI=1/C11H12O4/c1-8(12)15-10(11(13)14)7-9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,13,14)

Upstream product

• 828-01-3 phenyllactic acid 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 108-05-4 vinyl acetate 
• 150-30-1 Phenylalanine 
• 127-09-3 sodium acetate 

Downstream Products

• 13674-16-3 methyl 2-hydroxy-3-phenylpropanoate 
• 92702-58-4 α-Acetoxy-β-phenyl-propionsaeure-N,N-diaethylamid 
• 828-01-3 D-phenyllactic acid 
• 33173-31-8 (S)-3-phenyl-2-acetyloxypropionic acid 
• 1027336-35-1 C₁₆H₁₈O₇ 
• 110271-79-9 4-Benzyl-5-methoxy-[1,2,3]oxadiazole-2,3-dicarboxylic acid diisopropyl ester 
• 110271-83-5 C₁₈H₂₄N₂O₆ 
• 110271-88-0 (E)-2-(1-Methoxycarbonyl-2-phenyl-ethoxy)-3-phenyl-acrylic acid methyl ester 
• 151647-54-0 3-phenyl-1-pyrrolidin-1-yl-propane-1-one 
• 18859-19-3 N,N-diethyl-3-phenylpropanamide 
• 20312-36-1 L-3-phenyllactic acid 
• 868532-36-9 acetic acid 1-benzyl-2-oxo-2-(2-thioxo-oxazolidin-3-yl)-ethyl ester 
• 146235-25-8 (2R)-2-acetoxy-3-phenylpropanoic acid 
• 95393-19-4 2-acetoxy-3-phenylpropanoyl chloride 

Relevant academic research and scientific papers

CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS

The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula (I); where A1, A2, G, R1, R2, R3, R4, and W are described herein.

An efficient enzymatic aminolysis for kinetic resolution of aromatic α-hydroxyl acid in non-aqueous media

A new and highly efficient enzymatic aminolysis approach for kinetic resolution of aromatic α-hydroxy acid in non-aqueous media has been developed. The corresponding α-hydroxyl acid ester was employed as the substrate, and commercially available Candida antarctica lipase B is used as the biocatalyst, anhydrous ammonia is the resolving agent. Reactions can be proceeded smoothly in organic solvent at ambient temperatures. High concentration of substrate is allowed due to the application of organic media and the products are obtained in yields of up to 49% with ee values of up to 99%, and with E value of >300, representing an appealing and promising protocol for large-scale preparations.

Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): Tetramic, tetronic acids and dihydropyridin-2-ones

Based on a pharmacophore hypothesis substituted tetramic and tetronic acid 3-carboxamides as well as dihydropyridin-2-one-3-carboxamides were investigated as inhibitors of undecaprenyl pyrophosphate synthase (UPPS) for use as novel antimicrobial agents. S

Enantio-complementary deracemization of (±)-2-hydroxy-4- phenylbutanoic acid and (±)-3-phenyllactic acid using lipase-catalyzed kinetic resolution combined with biocatalytic racemization

Deracemization of (±)-3-phenyllactic acid (1) and (±)-2-hydroxy-4-phenylbutanoic acid (2) was accomplished by lipase-catalysed kinetic resolution coupled to biocatalytic racemization of the non-reacting substrate enantiomers using Lactobacillus paracasei DSM 20008. Cyclic repetition of this sequence led to a single enantiomeric product from the racemate. Access to both enantiomers was achieved by switching between lipase-catalysed acyl-transfer and ester hydrolysis reactions. Both products constitute important building blocks for virus protease- and ACE-inhibitors, respectively.

Novel nitrosation polymer in organic synthesis

The present invention relates to a novel nitrosation polymer of the formula in which X, Y, R1, R2 and R3 are as defined in claim 1. The invention also relates to a process for the preparation of the said polymer.

Kinetic resolution of α-acetoxy N-acyl oxazolidinethiones by a chiral O-nucleophilic acyl transfer catalyst

The kinetic resolution of α-acetoxy N-acyl oxazolidinethiones using the chiral, nonracemic O-nucleophilic acyl transfer catalyst 8 is described. The reaction proceeds on a variety of substrates in excellent yields, with s-factors ranging from 17 to 31. Copyright

Amino acid derivatives, the process for their preparation and their applications to therapy

Amino acid derivatives of formula (Ia) and (Ib) and prodrugs thereof containing a group responsible for chelating the zinc atom of enkephalinase and angiotensin convertase enzymes are disclosed as inhibitors of these enzymes.

Phenyl alpha acyloxyalkanoic acids, derivatives and their therapeutic use

Therapeutic as well as preventative measures to improve the cosmetic conditions or to alleviate the symptoms of dermatologic disorders with phenyl alpha acyloxyalkanoic acids and derivatives is disclosed. The cosmetic conditions and dermatologic disorders