6913-90-2

Upstream product

• 98-88-4 benzoyl chloride 
• 902779-63-9 (E)-N'-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide 
• 79-30-1 isobutyryl chloride 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 1297270-36-0 3-isopropyl-4,5-diphenyl-4H-1,2,4-triazole 
• 1380492-52-3 3-isopropyl-4-mesityl-5-phenyl-4H-1,2,4-triazole 
• 1380492-59-0 4-cyclohexyl-3-isopropyl-5-phenyl-4H-1,2,4-triazole 
• 1380492-60-3 4-butyl-3-isopropyl-5-phenyl-4H-1,2,4-triazole 
• 104217-22-3 2-phenyl-5-(propan-2-yl)-1,3,4-oxadiazole 

Relevant academic research and scientific papers

Light-emitting compound

A phosphorescent compound of formula (I): wherein M is a transition metal; L is a ligand; R1 is a branched C3-20 alkyl group, a cyclic C5-20 alkyl group or group of formula (II): wherein each R5 is aC1-10 alkyl group; each R6 is a substituent; z is 0 or a positive integer; R2 is a C1-10 alkyl group; R3 is a C1-10 alkyl group or a group of formula -(Ar1)p wherein Ar1 is aryl or heteroaryl group and p is at least 1; each R4 is independently a substituent; v is at least 1; w is 0 or a positive integer; x is at least 1; and y is 0 or a positive integer. The compound may be used as a blue light-emitting material in an organic light-emitting device.

Tunable protic ionic liquids as solvent-catalysts for improved synthesis of multiply substituted 1,2,4-triazoles from oxadiazoles and organoamines

More than green alternatives to traditional volatile molecular organic solvents, protic ionic liquids as dual solvent-catalysts have been successfully used to promote reactions of organoamines with oxadiazoles to afford sterically hindered 1,2,4-triazoles. Among the tested protic ionic liquids, pyridinium trifluoroacetate and acetate showed the highest efficiency for the reactions of arylamines and alkylamines, respectively, indicating that tunable catalysis could be readily effected with protic ionic liquid solvent-catalysts by simply tuning their cation and anion counterparts. A general and efficient approach has been developed for synthesis of multiply substituted 1,2,4-triazoles based on the tunable protic ionic liquid solvent-catalyst systems.

Reaction of 3-formylchromone-N-benzoylhydrazone with ketenes. Synthesis and structural studies of chromone 1,3,4-oxadiazolines

(Chemical Equation Presented) The reaction of 3-formylchromone-N- benzoylhydrazone with ketenes, prepared in situ from the corresponding acid chlorides 2a-d and the mixed anhydride 2e was studied. In all cases 2-(4′-oxo-4′H-3′-chromyl)-5-phenyl-2,3-dihydro-1,3, 4-oxadiazoles (3) were isolated in yields varying from 40 to 80%. A full structure assignment of all products has been made on the basis of 1D and 2-D (COSY H-H, COSY C-H, COLOC C-H) NMR spectra. A plausible reaction mechanism is also proposed based on theoretical approaches and experimental results.

4-Oxa and 4-thia steroids

The compounds of the present invention are those of structural formula (I) STR1 wherein X is oxygen or sulfur. Pharmaceutical compositions and methods of use of the compounds in the treatment of hyperandrogenic conditions are disclosed. In addition, the combination of the compounds with other active agents such as finasteride, minoxidil and retinoic acid or a derivative thereof is disclosed.