6919-62-6

Usage

Uses

Used in Organic Synthesis:
ETHYL N-METHOXY-N-METHYLCARBAMATE is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions, contributing to the production of a wide range of organic compounds.
Used in Pesticide and Herbicide Production:
In the agricultural industry, ETHYL N-METHOXY-N-METHYLCARBAMATE is utilized as an intermediate in the manufacturing of pesticides and herbicides, helping to control and eliminate unwanted plants and pests that can damage crops.
Used as a Solvent:
ETHYL N-METHOXY-N-METHYLCARBAMATE serves as a solvent in various industrial processes, including the dissolution of substances that are otherwise difficult to dissolve, thus aiding in the manufacturing of different products.
Used as a Stabilizer in Paints and Varnishes:
In the coatings industry, ETHYL N-METHOXY-N-METHYLCARBAMATE is used as a stabilizer in paints and varnishes to prevent the separation of components and ensure a uniform finish, enhancing the durability and performance of the final product.
Used as a Pharmaceutical Intermediate:
In the pharmaceutical sector, ETHYL N-METHOXY-N-METHYLCARBAMATE is employed as an intermediate in the synthesis of various drugs, playing a crucial role in the development of new medications and therapies.
Despite being classified as a low hazard chemical, it is essential to adhere to proper handling and storage procedures to ensure safety and minimize potential risks during its use in these applications.

InChI:InChI=1/C5H11NO3/c1-4-9-5(7)6(2)8-3/h4H2,1-3H3

Upstream product

• 589-41-3 ethyl N-hydroxylcarbamate 
• 77-78-1 dimethyl sulfate 
• 6919-58-0 Methoxy-methyl-(2,2-dimethyl-1-isopropyl-hydrazinomethyl)-amin 
• 541-41-3 chloroformic acid ethyl ester 
• 6919-46-6 bis(methoxymethylamino)methane 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 623-49-4 ethyl cyanoformate 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 74-88-4 methyl iodide 

Downstream Products

• 1117-97-1 N,0-dimethylhydroxylamine 
• 19437-26-4 2,2'-dipyridyl ketone 
• 502-56-7 nonanone-5 
• 119-61-9 benzophenone 
• 162468-75-9 Bis-[2-(4-methoxy-benzyl)-2H-pyrazol-3-yl]-methanone 

Relevant academic research and scientific papers

The Total Synthesis of Epothilone D as a Yardstick for Probing New Methodologies

Here, a concise and highly convergent synthesis of epothilone D was investigated, relying on fragments of equal complexity that could be prepared in gram scale quantities. The strategy to construct the fragments includes the use of a previously reported enantiospecific zinc-catalyzed cross-coupling of an α-hydroxy ester triflate with a Grignard reagent, the application of a hydroboration/boron–magnesium exchange sequence for the rapid construction of the Z-substituted trisubstituted double bond present in the natural product, and a Noyori-type hydrogenation to install the β-hydroxy ester moiety of the southern part. The key to success is the diastereoselective head-to-tail macrolactonization by an intramolecular addition of the corresponding ω-alkynyl-substituted carboxylic acids to construct a new stereocenter in the macrocyclic core structure in one single step.

Reactions of hydroxylamines with ethyl cyanoformate. Preparation of aminonitrones and their synthetic applications

The reaction of hydroxylamines with ethyl cyanoformate 1 leads to the formation of carbethoxyamino nitrones. 2. UV spectroscopy provided information that suggested the nitrone structure for these compounds in solution. X-ray analysis of 2a confirmed that it exists entirely in the nitrone form in the solid state. These nitrones are shown to be excellent starting materials for a variety of nitrogen containing compounds, namely, imidazoles, benzimidazoles, benzimidazolones, oxadiazolones, N-arylamidines and quinoxalone.

TANDEM ORGANOMETALLIC ADDITION REACTIONS TO N-METHOXY-UREAS AND URETHANES IN THE PREPARATION OF UNSYMMETRICAL AND SYMMETRICAL KETONES

The use of novel reagents 1a-c for the synthesis of ketones in a one pot reaction is described.An interesting leaving group effect was discovered in the fragmentation of the proposed complexes 2 to the intermediate N-methoxyamides 3.