Ring opening of a fatty epoxide by diethylacetamido malonate in basic medium by phase transfer catalysis or under microwave irradiation

Article abstract of DOI:10.1080/00397919408010188

A fatty epoxide (tetradecyl-oxirane) is reacted with diethyl acetamidomalonate in basic medium, with or without solvent under solid-liquid phase transfer catalysis with LiCl, or under microwave irradiation on supported reagents (KF/Al₂O₃/LiCl). The main product is a lactone which is formed after epoxide ring opening and subsequent cyclisation. We put here into evidence, for the first time, the conjugated advantages of 'dry media' reactions, lithium salt effects and microwave irradiation.

Full text of DOI:10.1080/00397919408010188

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Ring Opening of a Fatty
Epoxide by Diethylacetamido
Malonate in Basic Medium by
Phase Transfer Catalysis or
Under Microwave Irradiation
a
a
b
D. Abenhaïm , A. Loupy , C. Mahieu & D.
b
Séméria
a
Laboratoire des Réactions Sélectives sur Supports,
CNRS UA 478 ICMO, Université de Paris-Sud,
B[acaron]timent 410, 91405, Orsay Cedex, France
b
L'Oréal S.A., I, Avenue E. Schueller, 93601, Aulnay
sous Bois, France
Available online: 23 Sep 2006
To cite this article: D. Abenhaïm, A. Loupy, C. Mahieu & D. Séméria (1994): Ring
Opening of a Fatty Epoxide by Diethylacetamido Malonate in Basic Medium by Phase
Transfer Catalysis or Under Microwave Irradiation, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 24:13,
1809-1816
To link to this article: http://dx.doi.org/10.1080/00397919408010188
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