69200-91-5

Upstream product

• 122-78-1 phenylacetaldehyde 
• 100-63-0 phenylhydrazine 
• 110-86-1 pyridine 
• 5873-91-6 phenyldithioacetic acid 

Downstream Products

• 69200-92-6 (E)-1-phenyl-2-((E)-styryl)diazene 
• 33244-10-9 C₂₀H₁₈N₄ 
• 1504-16-1 3-phenyl-1H-indole 
• 30020-98-5 N-methyl-3-phenylindole 
• 1609470-49-6 C₂₂H₁₇F₂NO₂S 
• 122-78-1 phenylacetaldehyde 
• 413624-41-6 1-phenyl-2-(1-phenylpent-4-en-2-yl)hydrazine 
• 123230-82-0 C₂₁H₂₀N₂O₂S 
• 52444-41-4 5-(4-chloro-phenyl)-1,4-diphenyl-1H-pyrazole 
• 948-65-2 2-phenyl-indole 

Relevant academic research and scientific papers

Visible light-mediated C-H difluoromethylation of electron-rich heteroarenes

A novel method for visible-light photoredox-catalyzed difluoromethylation of electron-rich N-, O-, and S-containingheteroarenes under mild reaction conditions is developed. Mechanistic investigation indicates that the net C-H difluoromethylation proceeds through an electrophilic radical-type pathway.

Fast hydrazone reactants: Electronic and acid/base effects strongly influence rate at biological pH

Kinetics studies with structurally varied aldehydes and ketones in aqueous buffer at pH 7.4 reveal that carbonyl compounds with neighboring acid/base groups form hydrazones at accelerated rates. Similarly, tests of a hydrazine with a neighboring carboxylic acid group show that it also reacts at an accelerated rate. Rate constants for the fastest carbonyl/hydrazine combinations are 2-20 M-1 s-1, which is faster than recent strain-promoted cycloaddition reactions.