69212-31-3

Usage

General Description

2-(Benzylthio)-3-nitropyridine is a pyridine derivative.

InChI:InChI=1/C12H10N2O2S/c15-14(16)11-7-4-8-13-12(11)17-9-10-5-2-1-3-6-10/h1-8H,9H2

Upstream product

• 5470-18-8 2-Chloro-3-nitropyridine 
• 100-53-8 phenylmethanethiol 
• 584-08-7 potassium carbonate 
• 100-44-7 benzyl chloride 
• 2943-26-2 S-benzyl O-ethylxanthate 
• 100-39-0 benzyl bromide 
• 38240-29-8 3-nitro-2-mercaptopyridine 

Downstream Products

• 68206-45-1 3-nitro-2-pyridinesulfenyl chloride 
• 69212-32-4 2-(benzylthio)pyridin-3-amine 
• 250375-03-2 Boc-D-Pen(Npys)-OH 
• 82176-99-6 N-(((9H-fluoren-9-yl)methoxy)carbonyl)-S-((3-nitropyridin-2-yl)thio)-L-cysteine 
• 1071519-50-0 (1R,2S,7R,8S)-5-(1,1-dioxo-1,4-dihydro-1λ6-thia-2,4,8-triazanaphthalen-3-yl)-3-(4-fluorobenzyl)-6-hydroxy-3-azatricyclo[6.2.1.02,7]undec-5-en-4-one 
• 94527-46-5 3-aminopyridine-2-sulfonamide 

Relevant academic research and scientific papers

Xanthates as Thiol Surrogates for Nucleophilic Substitution with Aryl Halides

We herein report an unprecedented xanthate-based protocol for the preparation of aryl-alkyl thioethers. Heating xanthates with aryl halides and namely cesium carbonate in methanol provides the target thioethers in generally good yields within short reaction times. This method allows one to avoid contact with odorous thiols and also to introduce substituents of which the corresponding thiols are virtually unavailable or inconvenient in use.

FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY

A compound of formula (I): which inhibits the activity of one or more KATs of the MYST family, i.e., TIP60, KAT6B, MOZ, HBO1 and MOF.

Npys-Mediated Elimination Reactions of Alcohols and Thiols: A Facile Route to Dehydroalanine and Dehydrobutyrine Building Blocks

We report a new and rapid method for side-chain dehydration/dehydrothiolation of serine, threonine, and cysteine building blocks. The method relies on activation with 3-nitro-2-pyridinesulfenyl chloride (Npys-Cl) followed by treatment with base. It is pos

PYRIDINYL AND PYRIMIDINYL SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS

The present invention relates to novel pyridine or pyrimidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors. The invention relates specifically to the use of these compounds and their pharmaceutical compositions to treat disorders associated with chemokine receptor modulation.

Microwave-promoted "one-Pot" synthesis of 4- nitrobenzylthioinosine analogues using thiourea as a sulfur precursor

An efficient one-pot method for the synthesis of various C6-alkylthio-substituted purine nucleosides has been developed under microwave irradiation with good to excellent yields without any metal catalyst (see scheme). This process expands the scope of existing synthetic methodologies and was further successfully applied for synthesis of the biologically important compound 4-nitrobenzylthioinosine (NBTI).

Novel Sulfonaminoquinoline Hepcidin Antagonists

The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.

5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS

The invention is directed to 5,6-dihydro-lH-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

Antiretroviral compounds and compositions

Certain pyridine and quinoline derivatives' which inhibit replication of the retroviruses HIV-1, HIV-2 and human cytomegalovirus (HCMV) are provided. Pharmaceutical compositions useful in methods of treating or inhibiting certain retrovirus infections are

N-heteroartyl-n'-(pyrid-2yl-sulfonyl) ureas, processes for their preparation, and their use as herbicides and plant growth regulators

N-Heteroaryl-N'-(pyrid-2-yl-sulfonyl)ureas, processes for their preparation, and their use as herbicides and plant growth regulators Compounds of the formula (I) STR1 in which R1 -R4, A, n, m and w are as defined in claim 1, are suit

N-heteroaryl-N'-(pyrid-2-ylsulfonyl)ureas, processes for their preparation, and their use as herbicides and plant growth regulators

Compounds of the formula (I) or salts thereof STR1 in which R1 -R4, W, A, n and m are as defined in claim 1, for example R1 and R2 are H, (substituted) alkyl, (substituted) alkenyl or alkynyl, (substituted) cycl