69327-12-4

Basic information

• Product Name: 1-bromo-2-(2-bromoethyl)-4,5-dimethoxybenzene
• CAS NO: 69327-12-4
• Molecular Formula: C₁₀H₁₂Br₂O₂
• Molecular Weight: 324.0091
• Mol File: 69327-12-4.mol

Chemical Properties

• Boiling Point: 330.3°C at 760 mmHg
• Flash Point: 133.9°C
• Density: 1.623g/cm³
• Vapor Pressure: 0.000323mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 1-bromo-2-(2-bromoethyl)-4,5-dimethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-(2-bromoethyl)-4,5-dimethoxybenzene(69327-12-4)
• EPA Substance Registry System: 1-bromo-2-(2-bromoethyl)-4,5-dimethoxybenzene(69327-12-4)

Safety Data

• Hazardous Substances Data: 69327-12-4(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

The compound is derived from benzene, which is a basic structure consisting of a six-carbon ring with alternating single and double bonds.

Explanation

The compound contains two bromine atoms, which are halogen atoms that are covalently bonded to the benzene ring.

Explanation

Methoxy groups are derived from methanol (CH3OH) and are attached to the benzene ring through a covalent bond.

Explanation

The compound is used as a reagent or intermediate in the synthesis of various pharmaceuticals and agrochemicals.

Explanation

Due to its unique structure and properties, the compound has potential applications in the development of new drugs and agrochemicals.

Explanation

The compound is an important compound in the field of organic chemistry due to its potential applications and unique structure.

Explanation

The compound is used in the development of new materials and the study of chemical reactions, contributing to the advancement of organic chemistry.

Derivative of benzene

Yes

Number of bromine atoms

Two

Number of methoxy groups

Two

Common use

Organic synthesis and research

Potential applications

Pharmaceutical and agrochemical industries

Importance

Organic chemistry

Development

New materials and chemical reactions

Upstream product

• 289507-36-4 2-(2-bromo-4,5-dimethoxyphenyl)ethyl alcohol 
• 90841-59-1 2-(2-bromo-4,5-dimethoxyphenyl)acetaldehyde 
• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 
• 85362-72-7 N-<2-(3,4-Dimethoxyphenyl)-ethyl>-2,2-dimethylpropionsaeureimidchlorid Hydrochlorid 

Downstream Products

• 80536-55-6 6,7-Dimethoxy-2-trimethylsilanyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester 
• 80536-54-5 2-[2-(2-Bromo-ethyl)-4,5-dimethoxy-benzyl]-pentanedioic acid dimethyl ester 
• 63375-81-5 2-(2-bromo-4,5-dimethoxyphenylphenyl)ethan-1-amine 
• 80536-56-7 benzyl N-(1,2,3,4-tetrahydro-6,7-dimethoxynaphthalene-2-yl)carbamate 
• 13575-86-5 ADTN hydrobromide 
• 523-02-4 2,3,10,11-tetramethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[3,2-a]isoquinoline 
• 2934-97-6 (+/-)-tetrahydropalmatine 
• 289507-31-9 2-[2-(2-bromo-4,5-dimethoxyphenyl)ethyl]-7,8-(methylenedioxy)-1-oxo-1,2-dihydroisoquinoline 
• 289507-30-8 2-[2-(2-bromo-4,5-dimethoxyphenyl)ethyl]-6,7-(methylenedioxy)-1-oxo-1,2-dihydroisoquinoline 
• 289507-32-0 2-[2-(2-bromo-4,5-dimethoxyphenyl)ethyl]-6,7-dimethoxy-1-oxo-1,2-dihydroisoquinoline 
• 289507-12-6 2-[2-(2-bromo-4,5-dimethoxyphenyl)ethyl]-1-oxo-1,2-dihydroisoquinoline 
• 47206-72-4 2,3-dimethoxyberbine 
• 80536-53-4 methyl 6,7-dimethoxy-1,2,3,4-tetrahydro-2-naphthoate 

Relevant articles and documents

CuI-catalyzed coupling of gem-dibromovinylanilides and sulfonamides: An efficient method for the synthesis of 2-amidoindoles and indolo[1,2-a] quinazolines

A Cu(I)-catalyzed, intermolecular protocol for the synthesis of 2-amidoindoles and tetrahydroindolo[1,2-a]quinazolines in shorter time and high yields is reported. The key highlight of this disclosure is the formation of 2-amidoindole and tetrahydroindolo[1,2-a]quinazoline moieties directly from gem-dibromovinylanilides and sulfonamides in a one-pot fashion through the in situ formation of ynamides followed by a base-promoted intramolecular hydroamidation.

Aryl radical cyclizations: One-pot syntheses of protoberberine and pavine alkaloids

(equation presented) Treatment of 2-(2′-bromo-β-phenethyl)isocarbostyrils 7 with AIBN Bu3SnH in boiling benzene gave 8-oxoberbines 3 in good yields. A similar treatment of 2-(2′-bromo-β-phenethyl)isoquinolinium bromides 6 and their nor- and hom

The Mechanism of the Bischler-Napieralski Reaction, II: o-Chlorinated β-Phenethylamides as By-Products of the Ring Closure with PCl5

In addition to 3,4-dihydroisoquinolines o-chloro-β-phenethylamides are formed in the Bischler-Napieralski reaction using PCl5.Possible mechanisms for the chlorination were tested in model experiments.

A NEW SYNTHESIS OF 2-AMINO-6,7-DIHYDROXY-TETRAHYDRONAPHTHALENE (ADTN) VIA FUNCTIONALIZED ARYL-LITHIUM REAGENTS AND METHYL 2-TRIMETHYLSILYLACRYLATE - A NEW ANNULATION SEQUENCE

A new high yield synthesis of a potent dopamine agonist, 2-amino-6,7-dihydroxy-tetrahydronaphthalene, is described utilizing a new annulation sequence.