Welcome to LookChem.com Sign In|Join Free

CAS

  • or

69352-04-1

Post Buying Request

69352-04-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

69352-04-1 Usage

Uses

Different sources of media describe the Uses of 69352-04-1 differently. You can refer to the following data:
1. 1-?Chloro-?1,?3-?dihydro-?3,?3-?dimethyl-?1,?2-?benziodioxole is used as a reactant in one-pot preparation of hypervalent iodine(III)-CF3 reagent for the use in electrophilic trifluoromethylation reactions.
2. 1-Chloro-3,3-dimethylbenziodoxole is a crystalline, air-stable, yellow chloroiodane compound which finds use as a starting material for production of other hypervalent iodine compounds. It can also be used as a mild chlorinating reagent. The compound shows good solubility in polar organic solvents, typically dichloromethane or ethyl acetate.

Check Digit Verification of cas no

The CAS Registry Mumber 69352-04-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,3,5 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 69352-04:
(7*6)+(6*9)+(5*3)+(4*5)+(3*2)+(2*0)+(1*4)=141
141 % 10 = 1
So 69352-04-1 is a valid CAS Registry Number.

69352-04-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-chloro-3,3-dimethyl-1λ<sup>3</sup>,2-benziodoxole

1.2 Other means of identification

Product number -
Other names 1-chloro-3,3-dimethyl-1H-1,2-benziodoxole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69352-04-1 SDS

69352-04-1Relevant articles and documents

Iron-Catalyzed Enantioselective Radical Carboazidation and Diazidation of α,β-Unsaturated Carbonyl Compounds

Liu, Wen,Pu, Maoping,He, Jun,Zhang, Tinghui,Dong, Shunxi,Liu, Xiaohua,Wu, Yun-Dong,Feng, Xiaoming

supporting information, p. 11856 - 11863 (2021/08/16)

Azidation of alkenes is an efficient protocol to synthesize organic azides which are important structural motifs in organic synthesis. Enantioselective radical azidation, as a useful strategy to install a C-N3 bond, remains challenging due to the inherently instability and unique structure of radicals. Here, we disclose an efficient enantioselective radical carboazidation and diazidation of α,β-unsaturated ketones and amides catalyzed by chiral N,N′-dioxide/Fe(OTf)2 complexes. An array of substituted alkenes was transformed to the corresponding α-azido carbonyl derivatives in good to excellent enantioselectivities, benefiting the preparation of chiral α-amino ketones, vicinal amino alcohols, and vicinal diamines. Control experiments and mechanistic studies proved the radical pathway in the reaction process. The DFT calculations showed that the azido transferred to the radical intermediate via an intramolecular five-membered transition state with the internal nitrogen of the Fe-N3 species.

Oxidative cyanation of 2-oxindoles: formal total synthesis of (±)-gliocladin C

Bisai, Alakesh,Das, Mrinal Kanti,De, Subhadip,Maity, Arindam,Naskar, Malay,Roy, Avishek

supporting information, p. 1679 - 1684 (2020/03/05)

Efficient oxidative direct cyanations of 3-alkyl/aryl 2-oxindoles using Cyano-1,2-BenziodoXol-3(1H)-one (CBX) (2a) have been reported under 'transition metal-free' conditions to synthesize a wide variety of 3-cyano 3-alkyl/aryl 2-oxindoles sharing an all-carbon quaternary center under additive-free conditions. The application of this process is shown by the formal total synthesis of (±)-gliocladin C (11c) in a few steps.

Determining the predominant tautomeric structure of iodine-based group-transfer reagents by 17O NMR spectroscopy

Santschi, Nico,Pitts, Cody Ross,Jelier, Benson J.,Verel, René

, p. 2289 - 2294 (2018/09/14)

Cyclic benziodoxole systems have become a premier scaffold for the design of electrophilic transfer reagents. A particularly intriguing aspect is the fundamental II–IIII tautomerism about the hypervalent bond, which has led in certain cases to a surprising re-evaluation of the classic hypervalent structure. Thus, through a combination of 17O NMR spectroscopy at natural abundance with DFT calculations, we establish a convenient method to provide solution-phase structural insights for this class of ubiquitous reagents. In particular, we confirm that Shen’s revised, electrophilic SCF3-transfer reagent also adopts an "acyclic" thioperoxide tautomeric form in solution. After calibration, the approach described herein likely provides a more general and direct method to distinguish between cyclic and acyclic structural features based on a single experimental 17O NMR spectrum and a computationally-derived isotropic shift value. Furthermore, we apply this structural elucidation technique to predict the constitution of an electrophilic iodine-based cyano-transfer reagent as an NC–I–O motif and study the acid-mediated activation of Togni's trifluoromethylation reagent.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 69352-04-1