69380-84-3Relevant academic research and scientific papers
The first example of saccharin-lithium bromide catalysis: Direct synthesis of N-tosylimines from alcohols
Patel, Rajesh,Srivastava, Vishnu P.,Yadav, La Dhar S.
experimental part, p. 1610 - 1614 (2010/09/05)
The first procedure to access N-tosylimines directly from alcohols under mild and neutral conditions is reported. The protocol involves saccharin-lithium bromide-catalyzed oxidation of alcohols to aldehydes/ketones with chloramine-T followed by their condensation with the in situ generated oxidation by-product p-toluenesulfonamide in the same reaction vessel to afford N-tosylimines in 40-90% overall yields. The present work opens up a new and efficient synthetic route to N-tosyimines directly from alcohols in a one-pot procedure.
Gold catalysis: Switching the pathway of the furan-yne cyclization
Hashmi, A. Stephen K.,Rudolph, Matthias,Huck, Juergen,Frey, Wolfgang,Bats, Jan W.,Hamzic, Melissa
supporting information; experimental part, p. 5848 - 5852 (2009/12/06)
Changing tracks: By the use of alkynyl ethers as directing elements, the furan-yne cyclization enters a new reaction pathway. Instead of phenols, tetracycles containing two heteroatoms and two new stereocenters are formed (see scheme).
3,3-Disubstituted 2-Sulphonyloxaziridines: Synthesis and Observation of Isomeric Nitrogen Invertomers
Jennings, W. Brian,Watson, Stephen P.,Boyd, Derek R.
, p. 931 - 932 (2007/10/02)
The synthesis of the title compounds from oximes is described; some of these compounds provide the first reported examples of cis-trans isomerism in N-sulphonyloxaziridines.
