69390-84-7Relevant academic research and scientific papers
A facile and efficient synthesis of N-benzylazetidine
Lai
, p. 565 - 568 (2001)
An efficient, two-step synthesis of N-benzylazetidine, starting from benzaldehyde and 3-bromopropylamine hydrobromide, is described.
N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF
-
Page/Page column 47, (2008/06/13)
N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for
Mechanistic considerations for the consecutive cyclization of 2,3-dibromopropylamine hydrobromide giving a strained molecule, 1-azabicyclo[1.1.0]butane
Hayashi, Kazuhiko,Ikee, Yoshifumi,Goto, Satoru,Shiro, Motoo,Nagao, Yoshimitsu
, p. 89 - 94 (2007/10/03)
The effective formation of 1-azabicyclo[1.1.0]butane (2) by treatment of 2,3-dibromopropylamine hydrobromide (1) with n-BuLi could be understood considering a rational reaction pathway via both transition states 10 and 19 based on the intramolecular Br...
Method of inhibiting the growth of protozoa
-
, (2008/06/13)
α-Substituted amines and α-substituted-α-amino acids are described which are useful in inhibiting the growth of protozoa in animals.
Method of inhibiting algae
-
, (2008/06/13)
α-Substituted amines and α-substituted-α-amino acids are described which are useful in controlling the growth of algae.
α-Acetylenic derivatives of α-amino acids
-
, (2008/06/13)
Novel acetylenic derivatives of α-amino acids of the following general structure: STR1 wherein Z is β-methylthioethyl, β-benzylthioethyl, S-(5'-desoxyadenosin-5' -yl)-S-methylthioethyl, γ-guanidinopropyl, or RHN(CH2)n --; n is the integer 3 or 4; each R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched, or STR2 wherein R2 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; R1 is hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, --NR4 R5 wherein each of R4 and R5 is hydrogen or a lower alkyl group of from 1 to 4 carbon atoms, or STR3 wherein R3 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; and the lactams thereof when Z is RHN(CH2)n -- and each R is hydrogen; with the provisos that when Z is β-benzylthioethyl or S-(5'-desoxyadenosin-5' -yl)-S-methyl-thioethyl, R is hydrogen and R1 is hydroxy, when Z is γ-guanidinopropyl, R is hydrogen and R1 is hydroxy or a straight or branched lower alkoxy group of from 1 to 8 carbon atoms, and when Z is RHN(CH2)n -- both R groups are the same; and pharmaceutically acceptable salts and individual optical isomers thereof.
