69398-48-7

Usage

Uses

Used in Pharmaceutical Industry:
N-(Phenylsulfonyl)glycine Methyl Ester is used as a reagent for the synthesis of various pharmaceuticals, leveraging its potential biological activity and its role as a building block in drug discovery and development.
Used in Organic Synthesis:
In the field of organic synthesis, N-(Phenylsulfonyl)glycine Methyl Ester is utilized as a versatile reagent for the preparation of a diverse range of compounds, taking advantage of its stability and reactivity to facilitate chemical reactions and the creation of new molecules.

Upstream product

• 67-56-1 methanol 
• 5398-96-9 N-phenylsulfonylglycine 
• 50487-70-2 N-allylbenzenesulfonamide 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 265669-17-8 N-Phenylsulfonyl-α-bromoglycine methyl ester 
• 331731-75-0 (benzenesulfonyl-prop-2-ynyl-amino)-acetic acid methyl ester 
• 60160-52-3 phenylsulfonylaminoacetic acid hydrazide 
• 195380-04-2 N-allyl-N-(2-oxoethyl)benzenesulfonamide 
• 195380-06-4 N-(3-Methyl-but-2-enyl)-N-(2-oxo-ethyl)-benzenesulfonamide 
• 203204-46-0 N-((E)-4-Oxo-pent-2-enyl)-N-((E)-3-phenyl-allyl)-benzenesulfonamide 
• 69398-49-8 N-methoxycarbonylmethyl-N-trichloromethylthiobenzenesulfonamide 
• 317336-65-5 N-[1-(4-Chloro-phenyl)-meth-(E)-ylidene-hydrazinocarbonylmethyl]-benzenesulfonamide 
• 543725-66-2 N-[2-(3-methyl-5-oxo-4,5-dihydro-pyrazol-1-yl)-2-oxo-ethyl]-benzenesulfonamide 

Relevant academic research and scientific papers

Synthesis, characterization and antifungal activities of some benzenesulphonylamino acid derivatives

Condensation of benzenesulphonyl chloride (1) with a series of amino acids afforded benzenesulphonylamino acids (2a-d). Esterification of the derivatives (2a-d) in methanol gave the corresponding benzensulphonylamino acid methylesters (3a-d), which conden

Palladium catalysed tandem cyclisation-anion capture. Part 7: Synthesis of derivatives of α-amino esters, nitrogen heterocycles and β-aryl/heteroaryl ethylamines via in situ generated vinylstannanes

Palladium catalysed in situ hydrostannylation of terminal alkynes containing a β-N atom affords mainly α-vinylstannanes which serve as anion capture agents in palladium catalysed cyclisation-anion capture processes leading to derivatives of α-amino esters, nitrogen heterocycles and β-aryl/heteroaryl ethylamines in good yield.

Palladium-catalysed asymmetric allylic substitution: Synthesis of α- and β-amino acids

Methodology has been established for the formation of enantiomerically enriched α-amino acids using palladium-catalysed allylic amination. The formation of enantiomerically enriched allylamines has been achieved with high enantioselectivity. Oxidative cleavage of the allylamines provides arylglycine and glutamic acid derivatives. Additionally, enantiomerically enriched β-amino acids have been prepared in high enantiomeric excess. Palladium-catalysed asymmetric allylic substitution is used as the key synthetic transformation.

Fungicidal, miticidal and ovicidal alkoxycarbonylalkyl-substituted and carbamylalkyl-substituted N-haloalkylthiosulfonamides

Fungi, mites and mite eggs are killed by applying thereto sulfonamides of the formula STR1 wherein R and R1 individually are alkyl, cycloalkyl, aryl, carbamylalkyl, or alkoxycarbonylalkyl and R2 is haloalkyl, with the proviso that one R or R1 group is carbamylalkyl or alkoxycarbonylalkyl.