694489-60-6 Usage
Core Structure
Naphthyridine a fused nitrogen-containing ring system
Functional Group
Carboxylic acid a compound containing the -COOH group
Substituent
3-Boronophenyl a phenyl group with a boron atom attached to the 3rd carbon
Additional Structure
1,4-Dihydro indicating two hydrogen atoms added to the molecule
Oxidation State
4-Oxo a carbonyl group (C=O) present at the 4th position
Ester Functionality
3-Ethyl ester an ethyl group (C2H5) attached to the carboxylic acid via an ester linkage
Solubility
Enhanced by the ethyl ester group, potentially improving bioavailability
Applications
Potential use in medicinal chemistry, targeting enzymes or receptors
Research Interest
Pharmaceutical research and development, new therapeutic agents for various medical conditions
Further Studies
Required to understand biological activity, pharmacological properties, and potential uses
Check Digit Verification of cas no
The CAS Registry Mumber 694489-60-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,9,4,4,8 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 694489-60:
(8*6)+(7*9)+(6*4)+(5*4)+(4*8)+(3*9)+(2*6)+(1*0)=226
226 % 10 = 6
So 694489-60-6 is a valid CAS Registry Number.
694489-60-6Relevant academic research and scientific papers
Practical application of new catalytic methods: A concise synthesis of a potent PDE IV inhibitor
Albaneze-Walker, Jennifer,Murry, Jerry A.,Soheili, Arash,Ceglia, Scott,Springfield, Shawn A.,Bazaral, Charles,Dormer, Peter G.,Hughes, David L.
, p. 6330 - 6336 (2007/10/03)
An efficient synthesis of a potent PDE IV inhibitor 1 is described. The synthesis is highlighted by two practical and efficient catalytic reactions: a highly selective catalytic palladium mediated carbonylation of the pyridine side chain and an efficient
METHOD OF PREPARING INHIBITORS OF PHOSPHODIESTERASE-4
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Page 9, (2010/02/07)
In one aspect, the present invention is directed to a one pot method of preparing intermediates of Formula V, which are useful in making inhibitors of phosphodiesterase-4: The present invention is also directed to a method of preparing phosphodiesterase inhibitors comprising the Formula
