694489-62-8

Basic information

• Product Name: 1-{3-[6-(1-hydroxy-1-methylethyl)-1-oxidopyridin-3-yl]phenyl}-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxylic acid
• Synonyms: 1-{3-[6-(1-hydroxy-1-methylethyl)-1-oxidopyridin-3-yl]phenyl}-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxylic acid
• CAS NO: 694489-62-8
• Molecular Weight: 417.421
• Mol File: 694489-62-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-{3-[6-(1-hydroxy-1-methylethyl)-1-oxidopyridin-3-yl]phenyl}-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{3-[6-(1-hydroxy-1-methylethyl)-1-oxidopyridin-3-yl]phenyl}-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxylic acid(694489-62-8)
• EPA Substance Registry System: 1-{3-[6-(1-hydroxy-1-methylethyl)-1-oxidopyridin-3-yl]phenyl}-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxylic acid(694489-62-8)

Safety Data

• Hazardous Substances Data: 694489-62-8(Hazardous Substances Data)

Upstream product

• 85006-23-1 3-aminophenylboronic acid hydrochloric salt 
• 132308-19-1 methyl 5-chloropyridine-2-carboxylate 
• 49609-84-9 2-Chloronicotinoyl chloride 
• 694489-61-7 ethyl 1-{3-[6-(1-hydroxy-1-methylethyl)-1-oxido-pyridin-3-yl]phenyl}-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxylate 
• 694489-60-6 ethyl 1-(phenyl-3-dihydroxyboranyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxylate 
• 40472-78-4 3-chloro-2-(1-hydroxy-1-methylethyl)-pyridine 

Relevant articles and documents

Practical application of new catalytic methods: A concise synthesis of a potent PDE IV inhibitor

An efficient synthesis of a potent PDE IV inhibitor 1 is described. The synthesis is highlighted by two practical and efficient catalytic reactions: a highly selective catalytic palladium mediated carbonylation of the pyridine side chain and an efficient