69489-15-2

Basic information

• Product Name: Benzeneacetaldehyde, a-ethyl-a-hydroxy-, (S)-
• CAS NO: 69489-15-2
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Mol File: 69489-15-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, a-ethyl-a-hydroxy-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, a-ethyl-a-hydroxy-, (S)-(69489-15-2)
• EPA Substance Registry System: Benzeneacetaldehyde, a-ethyl-a-hydroxy-, (S)-(69489-15-2)

Safety Data

• Hazardous Substances Data: 69489-15-2(Hazardous Substances Data)

Upstream product

• 89556-33-2 2-<(1'S)-1'-hydroxy-1'-phenylpropyl>hexahydro-4,4,7-trimethyl-4H-1,3-benzoxathiin 
• 636599-74-1 (1S,2R,5R,7S,9R)-5-[(1'S)-1'-hydroxy-1'-phenylpropyl]-10,10-dimethyl-4-oxa-6-thiatricyclo[7.1.1.0^2,7]undecane 
• 2439-43-2 (2RS)-2-phenylbutanal 
• 872045-33-5 (1-methoxybut-1-en-2-yl)benzene 
• 93-55-0 1-phenyl-propan-1-one 
• 115156-57-5 (2S,4aS,7R,8aR)-2-benzoyl-N-benzyl-4,4,7-trimethyl-octahydro-1,3-benzoxazine 
• 1074-12-0 phenylglyoxal hydrate 
• 266694-57-9 Phenyl-((2R,4aR,7R,8aR)-4,4,7-trimethyl-hexahydro-1-oxa-3-thia-naphthalen-2-yl)-methanone 
• 682352-11-0 (1S,2R,3S,5R,2'R)-6,6-dimethyl-3-(2'-ethoxy-1'-phenyl-1'-oxo-2'-ethylsulfanyl)-2-(O-t-butyl-dimethylsilyl-hydroxymethyl)-bicyclo[3.1.1]heptane 
• 682352-09-6 (1S,2R,3S,5R,2'R)-6,6-dimethyl-3-(2'-ethoxy-1'-phenyl-1'-oxo-2'-ethylsulfanyl)-2-hydroxymethyl-bicyclo[3.1.1]heptane 
• 599192-45-7 (1S,2R,5R,7S,9R)-5-benzoyl-10,10-dimethyl-4-oxa-6-thiatricyclo[7.1.1.0^2,7]undecane 
• 6175-45-7 2,2-diethoxyacetophenone 
• 682352-20-1 (1S,2R,3S,5R,1'R,2'S)-6,6-dimethyl-3-(1'-ethoxy-2'-phenyl-2'-hydroxy-1'-butylsulfanyl)-2-(O-t-butyl-dimethylsilyl-hydroxymethyl)-bicyclo[3.1.1]heptane 
• 168961-28-2 (1S,2R,4S,6S,7R)-4-((S)-1-Hydroxy-1-phenyl-propyl)-7,10,10-trimethyl-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decane-5-carboxylic acid tert-butyl ester 

Downstream Products

• 24256-91-5 (S)-2-hydroxy-2-phenylbutanoic acid 
• 2404-42-4 (S)-(-)-2-phenyl-butane-1,2-diol 
• 3966-31-2 (R)-2-hydroxy-2-phenylbutyric acid 
• 76496-47-4 (S)-2-hydroxy-2-phenyl-butyric acid methyl ester 
• 89616-49-9 (R)-2-hydroxy-2-phenyl-butyric acid methyl ester 

Relevant articles and documents

A simple primary amine catalyst for enantioselective α-hydroxylations and α-fluorinations of branched aldehydes

A new primary amine catalyst for the asymmetric α-hydroxylation and α-fluorination of α-branched aldehydes is described. The products of the title transformations are generated in excellent yields with high enantioselectivities. Both processes can be performed within short reaction times and on gram scale. The similarity in results obtained in both reactions, combined with computational evidence, implies a common basis for stereoinduction and the possibility of a general catalytic mechanism for α-functionalizations. Promising initial results in α-amination and α-chlorination reactions support this hypothesis.

Lithium acetylides as alkynylating reagents for the enantioselective alkynylation of ketones catalyzed by lithium binaphtholate

Chiral lithium binaphtholate effectively catalyzed the enantioselective alkynylation of ketones using lithium acetylide as an alkynylating agent. This is the first example of the catalytic enantioselective addition of lithium acetylide to carbonyl compoun

Enantioselective synthesis of either enantiomer of α-alkyl-α- hydroxy-α-phenylacetic acids using chiral auxiliaries

The enantioselective synthesis of either enantiomer of α-alkyl- α-hydroxy-α-phenylacetic acids was achieved by using 2-acyloxathianes 1a-c and the mixed acyl-S,O-acetals 7 and 8 as chiral auxiliaries, which can straightforwardly be prepared from (1R)-(-)-myrtenal. This procedure allowed the preparation of the title compounds in >95% enantiomeric excess (ee).