6954-91-2Relevant articles and documents
Domino multicomponent approach for the synthesis of functionalized spiro-indeno[1,2-b]quinoxaline heterocyclic hybrids and their antimicrobial activity, synergistic effect and molecular docking simulation
Almansour, Abdulrahman I.,Arumugam, Natarajan,Kumar, Raju Suresh,Al-Thamili, Dhaifallah M.,Periyasami, Govindasami,Ponmurugan, Karuppiah,Al-Dhabi, Naif Abdullah,Perumal, Karthikeyan,Premnath, Dhanaraj
, (2019)
An expedient synthesis of hitherto unexplored novel hybrid heterocycles comprising dispiropyrrolidine, N-styrylpiperidone and indeno[1,2-b]quinoxaline units has been developed via domino multicomponent 1,3-dipolar cycloaddition strategy employing a new cl
Synthesis of new spiro compounds proceeding from 11H-Indeno[1,2-b]quinoxalin-2-one
Velikorodov,Stepkina,Shustova,Ionova
, p. 674 - 679 (2015)
Reaction of 11H-indeno[1,2-b]quinoxalin-2-one with semi(thiosemi)carbazides in ethanol resulted in semi(thiosemi)carbazones which at boiling in acetic anhydride underwent cylization yielding N-{3′-acetyl-3′H-spiro[indeno[1,2-b]quinoxalin-11,2′-[1,3,4]oxa(
One-pot three-component synthesis of novel spiroindenoquinoxalines
Chen, Feiran,Zheng, Jia,Huang, Mingming,Li, Yiqun
, p. 5545 - 5554 (2015)
Numerous new spiroindenoquinoxalines containing pyrano groups were synthesized via a one-pot, three-component reaction of indenoquinoxaline, malononitrile with various α-methylenecarbonyl compounds (β-diketones, pyrazolones) catalyzed by triethylamine.
Synthesis of new functionally substituted hetarylcarbamates from methyl {4-[(2E)-3-(4-methoxyphenyl)-prop-2-enoyl]phenyl}carbamate
Velikorodov,Stepkina
, p. 1788 - 1791 (2016)
Three-component condensation of methyl {4-[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]phenyl}- carbamate with ninhydrin and L-proline in methanol–water (10: 1) afforded methyl {4-[1,3-dioxo-1′- (4-methoxyphenyl)-1,1′,2′,3,5′,6′,7′,7a′-octahydrospiro[indene-2,3′
A synthesis of spirofuran-indenoquinoxalines via isocyanid-based one-pot four-component reaction
Sabouri, Nahid,Mahdavinia, Gholam Hossein,Notash, Behrouz
, p. 1040 - 1043 (2016)
A simple and versatile procedure for the combinatorial synthesis of (Z)-dialkyl-5-(alkylimino)-5H-spiro[furan-2,11′-indeno[1,2-b]quinoxaline]-3,4-dicarboxylates via the catalyst-free one-pot four-component reaction of ninhydrin, benzene-1,2-diamines, dial
Dispiropyrrolidinyl-piperidone embedded indeno[1,2-b]quinoxaline heterocyclic hybrids: Synthesis, cholinesterase inhibitory activity and their molecular docking simulation
Arumugam, Natarajan,Almansour, Abdulrahman I.,Kumar, Raju Suresh,Kotresha,Saiswaroop,Venketesh
, p. 2621 - 2628 (2019)
A small library of new class of dispiropyrrolidinyl-piperidone tethered indono[1,2-b]quinoxaline heterocyclic hybrids 7a–j were synthesized employing multicomponent 1,3-dipolar cycloaddition strategy in [bmim]Br. The azomethine ylide employed is first of
Domino synthesis of quinoxaline derivatives using SBA-Pr-NH2 as a nanoreactor and their spectrophotometric complexation studies with some metals ions
Ahmadi, Tahereh,Mohammadi Ziarani, Ghodsi,Bahar, Shahriyar,Badiei, Alireza
, p. 1153 - 1161 (2018)
Abstract: Amino-functionalized SBA-15 (SBA-Pr-NH2) with a pore size of 6?nm has been used as a basic nanocatalyst in the domino one-pot synthesis of quinoxaline derivatives via the four-component reaction of ninhydrin, 1,2-aryl-diamines, malono derivatives, and α-methylenecarbonyl compound using microwave irradiation. The solid basic catalyst plays a significant role in catalysis, and enhancing the rate and yield of the reaction, it can be easily handled and removed from the reaction mixture by simple filtration and also reused several times without substantial loss of reactivity. Moreover, the complexation reaction between quinoxaline as a model ligand and some metal ions including Cd2+, Co2+, Cu2+, Fe3+, Hg2+, Ni2+, Pb2+, and Zn2+ ions was examined spectrophotometrically in DMF solution at 25?°C. The formation constants of the resulting complexes were calculated from the computer fitting of the molar absorbance measurements in different mole ratios. The obtained data indicated that the stability constant of the resulting complexes varied in the following order Pb2+>?Hg2+>?Cd2+>?Ni2+>?Cu2+>?Fe3+>?Zn2+>?Co2+.
TiO2-mediated, one-pot, four-component 1,3-dipolar cycloaddition reaction: A facile synthesis of dispiro-pyrrolidine ring systems
Suresh Babu,Raghunathan
, p. 347 - 354 (2009)
An expedient regioselective synthesis of dispiroindenoquinoxaline pyrrolidine derivatives mediated by TiO2 in a one-pot, four-component 1,3-dipolar cycloaddition reaction is described. Copyright Taylor & Francis Group, LLC.
Br?nsted acid hydrotrope combined catalysis in water: a green approach for the synthesis of indoloquinoxalines and bis-tetronic acids
Kumbhar, Arjun,Kanase, Dhanaji,Mohite, Suhas,Salunkhe, Rajshri,Lohar, Trushant
, p. 2263 - 2278 (2021/03/31)
The present work describes the applications of Br?nsted acid hydrotrope combined catalyst (BAHC) as a mild, efficient and reusable catalyst for synthesis of indoloquinoxalines and bis-tetronic acids in water. Using BAHC, we synthesized many indoloquinoxal
Ultrasound-Promoted Synthesis of Spirocyclopropanes from Switchable Starting Materials via Azomethine Ylide [3+2]-Cycloaddition
Yavari, Issa,Sheikhi, Sara,Sheykhahmadi, Jamil,Taheri, Zohreh,Halvagar, Mohammad Reza
, p. 2057 - 2066 (2021/02/26)
An ultrasound-promoted green protocol to access a new series of spirocyclopropanes from indeno[1,2- b ]quinoxaline derivatives and azomethine ylides, generated in situ from the iodine-catalyzed reaction of acetophenones as well as of 2-methylquinoline with pyridine in the presence of a base, is described. These transformations proceed via a spirocyclopropanation reaction followed by elimination of pyridine. Clear evidence for the structure of a spirocyclopropane-linked indenoquinoxaline derivative was obtained from single-crystal X-ray analysis. The most important feature of this reaction is the fact it forms three stereogenic centers, one of which is quaternary, with excellent selectivity.