6956-33-8Relevant academic research and scientific papers
Synthesis of thiocarbohydrazones and evaluation of their in vitro antileishmanial activity
Muhammad, Munira T.,Ghouri, Nida,Khan, Khalid M.,Arshia,Choudhary, Muhammad I.,Perveen, Shahnaz
, p. 725 - 732 (2018/10/31)
Background: Leishmaniasis is a protozoan parasitic vector-borne disease which is endemic in 88 tropical countries. Infected sandfly is the main vector of this disease, while there are several other vectors, parasites, and reservoirs involved in the transm
Synthesis of novel triazoles, tetrazine, thiadiazoles and their biological activities
Al-Omair, Mohammed A.,Sayed, Abdelwahed R.,Youssef, Magdy M.
, p. 2591 - 2610 (2015/03/04)
An expedient synthesis of novel triazoles, tetrazine and thiadiazoles, using conveniently accessible and commercially available starting materials has been achieved. The synthesized compounds were characterized by spectroscopic and elemental analyses, and screened for their antibacterial activities against four different strains, namely E. coli, P. aeruginosa, S. aureus and B. megaterium. In particular, the compounds 5, 24 and 26h exhibited excellent antibacterial activities compared to the reference antibiotic. To get further insight about their behavior, these compounds were tested for their antioxidant activities via SOD-like activity, DPPH free radical scavenging activity, ABST and NO, which showed promising results. Furthermore, these compounds effectively promoted the cleavage of genomic DNA as well, in the absence of any external additives.
A hydrazine- and phosgene-free synthesis of tetrazinanones, precursors to 1,5-dialkyl-6-oxoverdazyl radicals
Bancerz, Matthew,Youn, Beom,Dacosta, Matthew V.,Georges, Michael K.
scheme or table, p. 2415 - 2421 (2012/05/31)
A complementary approach to published synthetic methods for tetrazinanones, precursors to verdazyl radicals, is described herein. This approach uses carbohydrazide, a commercially available reagent, as a common starting material. Unlike previous methods d
Simple bisthiocarbonohydrazones as sensitive, selective, colorimetric, and switch-on fluorescent chemosensors for fluoride anions
Han, Feng,Bao, Yuhui,Yang, Zhigang,Fyles, Thomas M.,Zhao, Jianzhang,Peng, Xiaojun,Fan, Jiangli,Wu, Yunkou,Sun, Shiguo
, p. 2880 - 2892 (2008/02/05)
Bisthiocarbonohydrazones are found to be a class of sensitive, selective, ratiometric. and colorimetric chemosensors for anions such as fluoride (F -) or acetate (Ac-). The sensitivities, or the binding constants of the sensors with
Synthesis and Structure of Some Thiazole Derivatives
Badawy, Mohammed A.,Abdel-Hady, Sayed A.,Ibrahim, Yehia A.
, p. 393 - 395 (2007/10/02)
The addition of thiosemicarbazones 1 to α-halo acids 2 is shown to give 2-hydrazino-2-thiazolin-4-ones 3 and not 3-substituted 2-imino-3-(methyleneimino)thiazolidin-4-ones 4.The independent synthesis of 2-thiazolin-4-one derivatives 3 is also described.
Synthesis and Characterization of Bis-thiocarbonohydrazones
Rajendran, G.,Jain, Sampat R.
, p. 680 - 682 (2007/10/02)
Several bis-thiocarbonohydrazones have been synthesized using improved methods.The compounds prepared have been characterized by elemental analyses, melting points, and IR and PMR spectra.
