6957-51-3

Basic information

• Product Name: 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
• Synonyms: 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid; Benzoic acid, 2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
• CAS NO: 6957-51-3
• Molecular Formula: C₁₁H₇NO₄
• Molecular Weight: 217.1776
• Mol File: 6957-51-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 418.4°C at 760 mmHg
• Flash Point: 206.8°C
• Density: 1.521g/cm³
• Vapor Pressure: 9.52E-08mmHg at 25°C
• Refractive Index: 1.668
• CAS DataBase Reference: 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid(6957-51-3)
• EPA Substance Registry System: 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid(6957-51-3)

Safety Data

• Hazardous Substances Data: 6957-51-3(Hazardous Substances Data)

Usage

Chemical Class

Pyrrole derivatives

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Anti-Cancer Properties

Has shown promising results in inhibiting the growth of cancer cells

Antioxidant Properties

Has been investigated for its potential antioxidant properties

Anti-Inflammatory Properties

Has been investigated for its potential anti-inflammatory properties

Further Research Needed

More research is needed to fully understand its potential uses and benefits.

Upstream product

• 62530-49-8 2-{[(2Z)-3-carboxyprop-2-enoyl]amino}benzoic acid 
• 108-31-6 maleic anhydride 
• 118-92-3 anthranilic acid 

Downstream Products

• 1379147-93-9 maleimido-benzoyl chloride 
• 1379147-94-0 2-(3-chloro-2,5-dioxopyrrolidin-1-yl)benzoyl chloride 
• 78-40-0 triethyl phosphate 
• 1379148-23-8 diethyl 3,9-dioxo-9,9a-dihydro-3H-pyrrolo[1,2-a]indol-9-ylphosphonate 
• 1379148-22-7 diethyl (1-chloro-3,9-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]indol-9a(9H)-yl)phosphonate 
• 1379148-25-0 diethyl (diethoxyphosphoryloxy)[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]methylphosphonate 
• 1379148-24-9 C₁₉H₂₈ClNO₉P₂ 
• 1379148-21-6 C₂₁H₃₁NO₉P₂ 
• 101413-76-7 3-Oxo-2,3-dihydro-1,4-benzothiazin-2-yl-acetyl-anthranilsaeure 
• 64191-05-5 2-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester 

Relevant articles and documents

A novel approach to isoindolo[2,1-a]indol-6-ones

A convenient route to isoindolo[2,1-a]indol-6-ones has been developed starting from the appropriate 2-(N-phthaloyl)benzoic acids. Formation of the acid chlorides with thionyl chloride followed by heating with triethyl phosphite in a suitable solvent resulted in a multistep reaction giving tetracyclic β-ketophosphonates that on reduction with sodium borohydride gave the required indolones in good overall yields. Analogous β-ketophosphonates were also prepared starting with N,N-(1,8-naphthaloyl)-2-aminobenzoic acid and 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acids although of these only the naphthaloyl product could be reduced with sodium borohydride without cleaving the amide bond in the ring system.