69640-22-8

Basic information

• Product Name: diethyl 2-methyl-5-phenyl-1H-pyrrole-3,4-dicarboxylate
• Synonyms: diethyl 2-methyl-5-phenyl-1H-pyrrole-3,4-dicarboxylate
• CAS NO: 69640-22-8
• Molecular Weight: 301.342
• Mol File: 69640-22-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: diethyl 2-methyl-5-phenyl-1H-pyrrole-3,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-methyl-5-phenyl-1H-pyrrole-3,4-dicarboxylate(69640-22-8)
• EPA Substance Registry System: diethyl 2-methyl-5-phenyl-1H-pyrrole-3,4-dicarboxylate(69640-22-8)

Safety Data

• Hazardous Substances Data: 69640-22-8(Hazardous Substances Data)

Upstream product

• 24512-96-7 ethyl (Z)-2-azido-3-phenylacrylate 
• 141-97-9 ethyl acetoacetate 
• 53256-19-2 ethyl (Z)-3-amino-3-phenylacrylate 
• 626-34-6 ethyl 3-aminobut-2-enoate 
• 61013-61-4 ethyl 2-azido-3-phenylacrylate 

Relevant articles and documents

Synthesis of highly substituted pyrroles via oxidative free radical reactions of β-aminocinnamates

Oxidative free radical reactions of β-aminocinnamates are described. Imine radicals produced by tetra-n-butylammonium cerium(IV) nitrate (TBACN) oxidation of enamines undergo efficient addition to the C-C double bond of β-aminocinnamates. This TBACN media

Orthogonal synthesis of pyrroles and 1,2,3-triazoles from vinyl azides and 1,3-dicarbonyl compounds

Tri- and tetrasubstituted N-H pyrroles were prepared by the simple treatment of vinyl azides with 1,3-dicarbonyl compounds in toluene at 100 °C via 2H-azirine intermediates generated in situ. When the reactions of vinyl azides and 1,3-dicarbonyl compounds were performed in DMF in the presence of a catalytic amount of K2CO3, 1-vinyl-1,2,3-triazoles were obtained via 1,3-dipolar cycloaddition. These methodologies exploited orthogonal modes of chemical reactivity of vinyl azides, which could be achieved by slight modification of the reaction conditions.