69673-81-0

Basic information

• Product Name: 1-oxo-1-p-tolylpropan-2-yl acetate
• Synonyms: 1-oxo-1-p-tolylpropan-2-yl acetate
• CAS NO: 69673-81-0
• Molecular Weight: 206.241
• Mol File: 69673-81-0.mol

Chemical Properties

• CAS DataBase Reference: 1-oxo-1-p-tolylpropan-2-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-oxo-1-p-tolylpropan-2-yl acetate(69673-81-0)
• EPA Substance Registry System: 1-oxo-1-p-tolylpropan-2-yl acetate(69673-81-0)

Safety Data

• Hazardous Substances Data: 69673-81-0(Hazardous Substances Data)

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 5337-93-9 4'-methylpropiophenone 
• 2749-93-1 1-methyl-4-(1-propyn-1-yl)benzene 
• 127-19-5 N,N-dimethyl acetamide 
• 64-19-7 acetic acid 

Downstream Products

• 15482-26-5 2-hydroxy-1-(4-methylphenyl)propan-1-one 

Relevant articles and documents

Sulfur-mediated difunctionalization of internal and terminal alkynes for the synthesis of α-acetoxy ketones

The sulfur-mediated difunctionalization of alkynes is reported to give α-acetoxy ketones in a one-pot operation under mild conditions with 19–92% yield. By using wet potassium acetate as both the aqueous base and nucleophilic reagent, both terminal alkynes and internal alkynes could be converted into the α-acetoxy ketone products.

Synthesis of α-acetoxy and formyloxy ketones by thallium(III) promoted α-oxidation

Treatment of ketones with thallium(III) triflate in amide solvents at 60°C for 30 min followed by addition of small amounts of H2O cleanly provided the corresponding α-acyloxy ketones.

A facile synthesis of secondary α-alkoxy or α-acetoxy aromatic ketones

The treatment of HNIB with aromatic ketones and subsequent solvolysis using alcohol or acetic acid in one-pot system makes it possible to give corresponding secondary α-alkoxy or α-acetoxy ketones in high yields.