6971-52-4Relevant articles and documents
Regiospecific and highly stereoselective formation of benzisochroman-6,9-quinones. Synthesis of (±)-ventilagone and (±)-ventiloquinone H
Blouin,Beland,Brassard
, p. 1466 - 1471 (1990)
An approach known to give regiospecific cycloadditions over a wide range of substrates has been applied to the synthesis of (±)-ventilagone and (±)-ventiloquinone H using a novel, electron-rich heterocyclic diene. The strategy provides for the sole format
Tuning the Reactivity of Peroxo Anhydrides for Aromatic C-H Bond Oxidation
Pilevar, Afsaneh,Hosseini, Abolfazl,?ekutor, Marina,Hausmann, Heike,Becker, Jonathan,Turke, Kevin,Schreiner, Peter R.
, p. 10070 - 10079 (2018/09/06)
Phenol moieties are key structural motifs in many areas of chemical research from polymers to pharmaceuticals. Herein, we report on the design and use of a structurally demanding cyclic peroxide (spiro[bicyclo[2.2.1]heptane-2,4′-[1,2]dioxolane]-3′,5′-dione, P4) for the direct hydroxylation of aromatic substrates. The new peroxide benefits from high thermal stability and can be synthesized from readily available starting materials. The aromatic C-H oxidation using P4 exhibits generally good yields (up to 96%) and appreciable regioselectivities.
IMIDAZOLIDINEDIONE DERIVATIVES
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, (2011/06/26)
The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.