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5-(3,3,3-trifluoro-1-propenyl) 2'-deoxyuridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 69819-96-1 Structure
  • Basic information

    1. Product Name: 5-(3,3,3-trifluoro-1-propenyl) 2'-deoxyuridine
    2. Synonyms: 5-(3,3,3-trifluoro-1-propenyl) 2'-deoxyuridine
    3. CAS NO:69819-96-1
    4. Molecular Formula: C12H13 F3 N2 O5
    5. Molecular Weight: 322.24
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 69819-96-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(3,3,3-trifluoro-1-propenyl) 2'-deoxyuridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(3,3,3-trifluoro-1-propenyl) 2'-deoxyuridine(69819-96-1)
    11. EPA Substance Registry System: 5-(3,3,3-trifluoro-1-propenyl) 2'-deoxyuridine(69819-96-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 69819-96-1(Hazardous Substances Data)

69819-96-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 69819-96-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,8,1 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 69819-96:
(7*6)+(6*9)+(5*8)+(4*1)+(3*9)+(2*9)+(1*6)=191
191 % 10 = 1
So 69819-96-1 is a valid CAS Registry Number.

69819-96-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-[(E)-3,3,3-trifluoroprop-1-enyl]pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names (E)-5-(3,3,3-Trifluoro-1-propenyl)-2'-deoxyuridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69819-96-1 SDS

69819-96-1Downstream Products

69819-96-1Relevant articles and documents

Synthesis of (E)-5-(3,3,3-Trifluoro-1-propenyl)-2'-deoxyuridine and Related Analogues: Potent and Unusually Selective Antiviral Activity of (E)-5-(3,3,3-Trifluoro-1-propenyl)-2'-deoxyuridine against Herpes Simplex Virus Type 1

Bergstrom, Donald E.,Ruth, Jerry L.,Reddy, P. Anantha,Clercq, Erik De

, p. 279 - 284 (2007/10/02)

Syntheses of (E)-5-(3,3,3-trifluoro-1-propenyl)-2'-deoxyuridine (TFPe-dUrd) (1), 5-(3,3,3-trifluoro-1-propyl)-2'-deoxyuridine (11), 5-(3,3,3-trifluoro-1-methoxy-1-propyl)-2'-deoxyuridine (8), and 5-(3,3,3-trifluoro-1-hydroxy-1-propyl)-2'-deoxyuridine (10) from 5-chloromercuri-2'-deoxyuridine are described.The antiviral activity of TFPe-dUrd was determined in cell culture against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and vaccinia virus and compared concurrently with 5-(1-propenyl)-2'-deoxyuridine, 5-(2-bromovinyl)-2'-deoxyuridine,5-iodo-2'-deoxyuridine, and 5-(trifluoromethyl)-2'-deoxyuridine.TFPe-dUrd demonstrated a potent and unusually selective activity against HSV-1, with a 2-log reduction in virud yield at 0.03 μg/mL (0.09 μM); L-1210 cell growth was inhibited by 50percent only at 290 μg/mL.Isopycnic centrifugation of 32P-labeled DNA indicated that if 0.5 or 2 μM TFP3-dUrd was present for 0-6 h postinfection, viral DNA synthesis was reduced by ca. 50 and 85percent, respectively; concomitantly, a new DNA band appeared at lower density than normal cellular or viral DNA.

C-5 Substituted uracil nucleosides

-

, (2008/06/13)

Compounds of the formula STR1 wherein Ro is --CH=CH--CH3 or --CH=CH--CF3 and R is β-D-ribofuranosyl, β-D-2-deoxyribofuranosyl or β-D-arabinofuranosyl are useful as antiviral agents.

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