6982-72-5

Usage

Uses

Used in Fragrance and Flavor Industry:
Ethanone, 1-(5-methyl-1H-pyrrol-2-yl)is used as a fragrance ingredient for its floral, fruity, and sweet aroma, enhancing the scent profiles of perfumes and other fragranced products.
Used in Food Industry:
In the food industry, Ethanone, 1-(5-methyl-1H-pyrrol-2-yl)is used to add or enhance the characteristic aroma of various fruits and vegetables, contributing to the overall sensory experience of the food products.
Used in Pharmaceutical Production:
Ethanone, 1-(5-methyl-1H-pyrrol-2-yl)is utilized in the production of pharmaceuticals, where its unique properties may contribute to the development of new drugs or the improvement of existing ones.
Used as a Chemical Intermediate in Organic Synthesis:
In the field of organic synthesis, Ethanone, 1-(5-methyl-1H-pyrrol-2-yl)serves as a valuable chemical intermediate, facilitating the creation of a range of organic compounds for various applications.

Upstream product

• 636-41-9 2-methyl-1H-pyrrole 
• 60-29-7 diethyl ether 
• 506-96-7 Acetyl bromide 
• 925-90-6 ethylmagnesium bromide 
• 127-19-5 N,N-dimethyl acetamide 
• 127-09-3 sodium acetate 
• 108-24-7 acetic anhydride 
• 90005-93-9 2-acetyl-5-methyl-pyrrole-3-carboxylic acid 
• 1073-23-0 2,6-lutidine N-oxide 

Relevant academic research and scientific papers

Synthese und Photoisomerisierung von sterisch gehinderten 2,6-Dialkylpyridin-N-oxiden

Synthesis of the new sterically hindered pyridine-1-oxides 2c and 6a-c is described.Copper(II)-catalyzed photolysis of 2 and 6a in aqueous medium provides only small amounts of 2-acylpyrroles 8 and 10a together with by-products.Exclusive formation and better yields of 10 can be received upon irradiation of 6 in none protic solvents at low temperature.Introduction of bulky substituents as in 6 failed to stabilize any of the postulated intermediates in order to be identified during photoreaction.It is assumed that the high rate of polymerization is caused by unstable 1,3-oxazepines like 13.

PHOTOCHEMISTRY OF PYRIDINE N-OXIDES. TRAPPING OF AN INTERMEDIATE WITH AMINES

The photochemistry of pyridine N-oxide (1a) and the corresponding 4-benzyl (1b), 4-phenyl (1c), and 2,6-dimethyl (1d) derivatives has been investigated or reinvestigated.Substrates 1a and 1b yield a small amount of the corresponding 2-acylpyrroles (5a,b) as the only isolable product, 1d yields 5d in moderate yield and 1c yields 5c in aprotic and the 2-pyridone 7c in protic solvents.In the presence of diethylamine isomeric 5-diethylaminopentadienenitriles (3,4) are obtained in moderate yield along with deoxygenated pyridines (6).Under this condition no 5 is formed, but the yield of 7 is unchanged.These reactions are most economically accunted for by admitting that nitrene 11 is formed as an intermediate and undergoes rearrangement to pyrroles 5 or polymerization to tars, or it can be trapped by amines (proton abstraction followed by nucleophilic substitution) to yield products 3 and 4.The lactams 7 arise directly from the N-oxide singlet excited state, which is also involved in the deoxygenation by amines.

Intramolecular Thermal Oxidoreduction of N-(2-Hydroxypropyl)-β-enaminoesters: Synthesis of N-(Acetonyl)-β-enaminoaldehydes and 2-Acetylpyrroles

Flow pyrolysis of the β-enaminoesters (1) provides the enaminoaldehydes (2), resulting from intramolecular oxidoreduction, and the acetylpyrroles (3); their relative yields depend on the temperature range.