699-43-4

Basic information

• Product Name: Cyclohexaneacetonitrile, 1-fluoro--alpha--hydroxy-
• Synonyms: Cyclohexaneacetonitrile, 1-fluoro--alpha--hydroxy-
• CAS NO: 699-43-4
• Molecular Formula: C₈H₁₂FNO
• Molecular Weight: 157.19
• Mol File: 699-43-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclohexaneacetonitrile, 1-fluoro--alpha--hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexaneacetonitrile, 1-fluoro--alpha--hydroxy-(699-43-4)
• EPA Substance Registry System: Cyclohexaneacetonitrile, 1-fluoro--alpha--hydroxy-(699-43-4)

Safety Data

• Hazardous Substances Data: 699-43-4(Hazardous Substances Data)

Upstream product

• 36929-66-5 1-oxaspiro<2,5>octane-2-carboxylic acid nitrile 
• 108-94-1 cyclohexanone 

Downstream Products

• 117169-36-5 <(5E,Z),(13E)>-15-(1-Fluorocyclohexyl)-11α,(15R)-dihydroxy-ω-pentanor-9a-carbaprostacyclin 
• 117169-36-5 <(5E,Z),(13E)>-15-(1-Fluorocyclohexyl)-11α,(15S)-dihydroxy-ω-pentanor-9a-carbaprostacyclin 
• 117169-35-4 1-exo-<3-(1-Fluorocyclohexyl)-3(R)-hydroxy-(E)-1-propenyl>-2-endo-hydroxy-5-oxooctahydropentalene 
• 117169-35-4 1-exo-<3-(1-Fluorocyclohexyl)-3(S)-hydroxy-(E)-1-propenyl>-2-endo-hydroxy-5-oxooctahydropentalene 
• 117189-39-6 5,5-(1,2-Ethanediyldioxy)-1-exo-<3-(1-fluorocyclohexyl)-3-oxo-(E)-1-propenyl>-2-endo-(tetrahydropyran-2-yloxy)octahydropentalene 
• 117169-34-3 C₂₄H₃₇FO₅ 
• 117169-33-2 dimethyl [2-(1-fluorocyclohexyl)-2-oxoethyl]phosphonate 
• 117169-32-1 Methyl 1-fluorocyclohexanecarboxylate 
• 117169-31-0 1-Fluorocyclohexanecarboxylic acid 
• 79205-63-3 (fluoro-1 cyclohexyl) glycolle 
• 83611-29-4 2-(1-fluorocyclohexyl)-2-ketoethanoic acid 
• 117169-30-9 1-Fluoro-1-hydroxymethylcyclohexane 
• 79205-59-7 2-amino-2-(1-fluorocyclohexyl)ethanonitrile 

Relevant articles and documents

1-Fluorocycloalkanecarboxylic acids in the synthesis of 16-achiral 16-fluoro-9a-carbaprostacyclin derivatives

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NEW SYNTHETIC ROUTES TO β-FLUORO β-PHENYLLACTIC ACID DERIVATIVES AND Β-FLUOROCYANOHYDRINS

Alkyl phenyl 2,3-epoxycarboxylates from the well-known Darzens glycidic esters synthesis react under very mild conditions with pyridinium-poly-hydrogen fluoride to give corresponding 3-fluoro 3-phenyllactates in almost quantitative yields with a high regio and stereoselectivity.This method can be applied succesfully to other flycidic derivatives: glycidoamides, glycidonitriles, glycidoiminoesters...The spectrometric properties (IR, NMR) are presented.