69905-97-1

Basic information

• Product Name: 2-(methyl(phenyl)amino)propanenitrile
• Synonyms: 2-(methyl(phenyl)amino)propanenitrile
• CAS NO: 69905-97-1
• Molecular Weight: 160.219
• Mol File: 69905-97-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-(methyl(phenyl)amino)propanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(methyl(phenyl)amino)propanenitrile(69905-97-1)
• EPA Substance Registry System: 2-(methyl(phenyl)amino)propanenitrile(69905-97-1)

Safety Data

• Hazardous Substances Data: 69905-97-1(Hazardous Substances Data)

Upstream product

• 78-97-7 2-hydroxy-propionitrile 
• 100-61-8 N-methylaniline 
• 676-58-4 methylmagnesium chloride 
• 132431-15-3 2-(N-methylanilino)-2-phenylsulfanylacetonitrile 
• 613-97-8 N-methyl-N-ethylaniline 
• 143-33-9 sodium cyanide 
• 36602-08-1 (N-methylanilino)acetonitrile 
• 107-13-1 acrylonitrile 
• 64-17-5 ethanol 
• 7677-24-9 trimethylsilyl cyanide 
• 62-53-3 aniline 
• 773837-37-9 sodium cyanide 
• 93-61-8 N-methyl-N-phenylformamide 

Downstream Products

• 20916-50-1 N-Methyl-N-(methyl-1)propen-1ylanilin 
• 69905-88-0 2-Methyl-2-(methyl-phenyl-amino)-butyronitrile 
• 98-04-4 phenyltrimethylammonium iodide 
• 74-90-8 hydrogen cyanide 

Relevant articles and documents

Iron-catalysed sequential reaction towards α-aminonitriles from secondary amines, primary alcohols and trimethylsilyl cyanide

We have developed a one-pot iron-catalysed sequential reaction of secondary amines with primary alcohols, trimethylsilyl cyanide and TBHP under mild reaction conditions to give the corresponding α-aminonitriles.

Covalently hooked EOSIN-Y in a Zr(IV) framework as visible-light mediated, heterogeneous photocatalyst for efficient C–H functionalization of tertiary amines

Herein, we report the synthesis of a novel heterogeneous photo-catalyst by utilizing post-synthetic modification of an amine functionalized Zr(IV) metal-organic framework (UiO-66-NH2) through covalent hooking of EOSIN-Y via dehydrating coupling. The characterization of the catalyst was accomplished by FT-IR, XRD, BET surface analysis, TGA, as well as TEM, SEM, XPS, DRS-UV–visible, and NMR spectroscopy, confirming successful covalent linking of EOSIN-Y with the pendent –NH2 functionality in the framework. That post-modified EY@UiO-66-NH2 acts as simple and green visible light mediated photo-catalyst for the C–H activation of tertiary amines with excellent yields. Importantly, the activity of dye incorporated heterogeneous photo-catalyst is found superior to that for the homogeneous photo-catalyst EOSIN-Y. Thus, separation difficulty of homogeneous catalysis, as well as the environmental adverse effects of toxic EOSIN-Y can be excluded by developing such photo-catalyst. Moreover, EY@UiO-66-NH2 catalyst could be consistently recycled up to 10 cycles, without any significant loss in activity. Based on literature report and experimental findings, we also propose a plausible mechanism for the reaction.

Ruthenium-catalyzed oxidative cyanation of tertiary amines with hydrogen peroxide and sodium cyanide

(Chemical Equation Presented) Versatile intermediates for the synthesis of N-aryl-α-amino acids and N,N-disubstituted 1,2-diamines can now be synthesized with high efficiency by the ruthenium-catalyzed oxidative cyanation of tertiary amines. The use of hy