700-47-0

Basic information

• Product Name: 4-HYDROXYPTERIDINE
• Synonyms: IFLAB-BB F2124-0196;4-HYDROXYPTERIDINE;4-PTERIDINOL;pteridin-4-ol;4(1H)-Pteridinone (9CI);4-PTERIDINOL 98%;4-HYDROXYPTERIDINE 98%;Pteridine-4(1H)-one
• CAS NO: 700-47-0
• Molecular Formula: C₆H₄N₄O
• Molecular Weight: 148.12
• EINECS: 211-845-1
• Product Categories: PYRIMIDINE
• Mol File: 700-47-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: >350 °C
• Boiling Point: 268.68°C (rough estimate)
• Flash Point: 175.5°C
• Appearance: /
• Density: 1.4122 (rough estimate)
• Vapor Pressure: 1.46E-05mmHg at 25°C
• Refractive Index: 1.6900 (estimate)
• Storage Temp.: 2-8°C
• PKA: pK1:1.3(＋1);pK2:7.89(0) (25°C)
• Water Solubility: 4.975g/L(20 oC)
• CAS DataBase Reference: 4-HYDROXYPTERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXYPTERIDINE(700-47-0)
• EPA Substance Registry System: 4-HYDROXYPTERIDINE(700-47-0)

Safety Data

• Hazardous Substances Data: 700-47-0(Hazardous Substances Data)

Usage

General Description

4-HYDROXYPTERIDINE is a chemical compound that is a derivative of pteridine and is a key component in the synthesis of biopterin, a vital cofactor for several essential enzymes in the human body. It is also an intermediate in the biosynthesis of tetrahydrobiopterin, which is crucial for the conversion of amino acids and the production of neurotransmitters. 4-HYDROXYPTERIDINE is found in various tissues and fluids in the body and plays a crucial role in maintaining normal physiological processes and overall health.

InChI:InChI=1/C6H4N4O/c11-6-4-5(9-3-10-6)8-2-1-7-4/h1-3H,(H,8,9,10,11)

Upstream product

• 32587-10-3 3-aminopyrazine-2-carboxamide 
• 122-51-0 orthoformic acid triethyl ester 
• 34859-38-6 2-Cyano-3-<(dimethylaminomethylene)amino>pyrazine 
• 67-56-1 methanol 
• 86805-19-8 4-(N,N-dimethylaminomethyleneamino)pteridine 3-oxide 
• 76952-40-4 4-aminopteridine 3-oxide 
• 76952-35-7 2-aminopyrazine-3-carboxamide oxime 
• 25911-65-3 2-amino-3-pyrazinonitrile 
• 76952-41-5 N-Pteridin-4-yl-hydroxylamine 
• 1672-50-0 5,6-diamino-4(3H)-pyrimidinone 
• 30564-38-6 4-methoxy-pteridine 
• 131543-46-9 Glyoxal 
• 14131-04-5 dimethyl-pteridin-4-yl-amine 
• 6973-01-9 4-aminopteridine 

Downstream Products

• 5424-01-1 3-aminopyrazinoic acid 
• 72700-48-2 4-chloro-pteridine 
• 1268607-25-5 [2-(4-benzyloxyphenyl)-ethyl]-pteridin-4-yl-amine 
• 487-21-8 Lumazine 
• 49539-13-1 5,6,7,8-tetrahydropteridin-4(3H)-one 
• 24851-65-8 3-methyl-3H-pteridin-4-one 
• 30564-38-6 4-methoxy-pteridine 

Relevant articles and documents

Electrochemical synthesis of quinazolinone: via I2-catalyzed tandem oxidation in aqueous solution

The development of protocols for synthesizing quinazolinones using biocompatible catalysts in aqueous medium will help to resolve the difficulties of using green and sustainable chemistry for their synthesis. Herein, using I2 in coordination with electrochemical synthesis induced a C-H oxidation reaction which is reported when using water as the environmentally friendly solvent to access a broad range of quinazolinones at room temperature. The reaction mechanism strongly showed that I2 cooperates electrochemically promoted the oxidation of alcohols, then effectively cyclizing amides to various quinazolinones.

NEW TYPE OF TRANSFORMATION OF A 1,2,4-TRIAZINE RING TO PYRAZINE DERIVATIVES

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SOME NEW SYNTHETIC APPROACHES FOR THE PREPARATION OF PTERIDINE-3-OXIDES AND PTERIDINES

Starting from 2-amino-3-cyanopyrazine some new syntheses of 4-substituted pteridines and pteridine-3-oxides have been devised.