70004-05-6Relevant articles and documents
Sulfoxidation of alkenes and alkynes with NFSI as a radical initiator and selective oxidant
Zhang, Yuexia,Wong, Zeng Rong,Wu, Xingxing,Lauw, Sherman J. L.,Huang, Xuan,Webster, Richard D.,Chi, Yonggui Robin
supporting information, p. 184 - 187 (2016/12/27)
Sulfoxides are important functional molecules. We develop a short-route (one-pot) synthesis of this class of molecules by reacting thiols with alkenes or alkynes under mild and metal-free conditions. N-Fluorobenzenesulfonimide (NFSI) is used to play dual roles: as a radical initiator for a thiol-ene/-yne reaction to form sulfide adducts, and as efficient oxidant for conversion of the sulfides formed in situ to sulfoxides. Over-oxidation of the sulfoxides to sulfones is avoided in our approach.
Reinheckel protocol revisited: Synthesis of (E)-α,β-unsaturated sulfoxides
Signore, Giovanni,Samaritani, Simona,Malanga, Corrado,Menicagli, Rita
, p. 762 - 764 (2007/10/03)
A new synthetic approach to aryl and alkyl α,β-unsaturated sulfoxides is reported. The reaction has been optimized with respect to solvent, temperature, and ratio of reagents. The described procedure allows the synthesis of the title compounds in good yie
