701-07-5

Basic information

• Product Name: 2-(2'-BROMOPHENOXY)PROPANE
• Synonyms: 2-BROMOISOPROPOXYBENZENE;2-(2'-BROMOPHENOXY)PROPANE;O-BROMOISOPROPOXYBENZENE;1-Bromo-2-isopropoxybenzene;1-Bromo-2-isopropoxybenzen
• CAS NO: 701-07-5
• Molecular Formula: C₉H₁₁BrO
• Molecular Weight: 215.09
• Product Categories: Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds
• Mol File: 701-07-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 73 °C / 2mmHg
• Flash Point: 128.2 °C
• Appearance: /
• Density: 1.34
• Vapor Pressure: 0.0837mmHg at 25°C
• Refractive Index: 1.5360-1.5400
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 2-(2'-BROMOPHENOXY)PROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2'-BROMOPHENOXY)PROPANE(701-07-5)
• EPA Substance Registry System: 2-(2'-BROMOPHENOXY)PROPANE(701-07-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 701-07-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

1-Bromo-2-isopropoxybenzene is used as an intermediate in organic syntheses.

InChI:InChI=1/C9H11BrO/c1-7(2)11-9-6-4-3-5-8(9)10/h3-7H,1-2H3

Upstream product

• 75-30-9 2-iodo-propane 
• 95-56-7 2-hydroxybromobenzene 
• 108-95-2 phenol 
• 75-26-3 isopropyl bromide 
• 187737-37-7 propene 

Downstream Products

• 946605-56-7 C₁₉H₂₉NO₄ 
• 1374633-35-8 tris(2-isopropoxyphenyl)phosphine 
• 1334215-84-7 C₆H₅COCHP(C₆H₄OCH(CH₃)2)3 
• 138008-97-6 2-isopropoxyphenylboronic acid 
• 63635-26-7 2-isopropoxybenzoic acid 

Relevant articles and documents

Catalytic Enantioselective Synthesis of Axially Chiral Diarylmethylidene Indanones

We describe the first atropselective Suzuki-Miyaura cross-coupling of β-keto enol triflates to access axially chiral (Z)-diarylmethylidene indanones (DAIs). The chemical, physical, and biological properties of DAIs are unknown, despite their being structurally similar to arylidene indanones, primarily due to the lack of racemic or chiral methods. Through this work, we demonstrate a general and efficient protocol for the racemic as well as the atropselective synthesis of (Z)-DAIs. An unusual intramolecular Morita-Baylis-Hillman reaction is utilized for the Z-selective synthesis of β-keto enol triflates.

Analogues of fenarimol are potent inhibitors of trypanosoma cruzi and are efficacious in a murine model of chagas disease

We report the discovery of nontoxic fungicide fenarimol (1) as an inhibitor of Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, and the results of structure-activity investigations leading to potent analogues with low nM IC50s in a T. cruzi whole cell in vitro assay. Lead compounds suppressed blood parasitemia to virtually undetectable levels after once daily oral dosing in mouse models of T. cruzi infection. Compounds are chemically tractable, allowing rapid optimization of target biological activity and drug characteristics. Chemical and biological studies undertaken in the development of the fenarimol series toward the goal of delivering a new drug candidate for Chagas disease are reported.

(Phenylpiperidinyl)cyclohexylsulfonamides: Development of α1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS)

Although α1 adrenergic receptor blockers can be very effective for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS), their usage is limited by CV-related side-effects that are caused by the subtype non-selec