70122-38-2

Upstream product

• 39070-63-8 4-benzoylbenzene-1,2-diamine 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 70122-39-3 C₂₄H₂₁N₃O₄S 
• 129545-19-3 (2-(4-methoxyphenyl)-1H-benzo[d]imidazol-5-yl)(phenyl)methanone 
• 70122-40-6 C₂₅H₂₃N₃O₄S 

Relevant academic research and scientific papers

Synthesis of some fused benzimidazole heterocyclic derivatives

Condensation of 3,4-diaminobenzophenone (1) with different aromatic aldehydes, under different conditions, gave only the corresponding mononail 2(a-d) and benzimidazole derivatives 3(a-d) without formation of the dianil. The monoanil 2(a) reacted with chloroacetyl chloride to give a mixture of 2-chloromethyl-5-benzoylbenzimidazole (4) and dibenzimidazolylethane derivative 5. The diamine 1 reacted with dimethylacetylenedicarboxylate to give the benzodiazepine-2-one derivative 6. On the other hand, 5-benzoyl-2-mercaptobenzimidazole (7) reacted with bromine, chloroacetic acid, chloroacetyl chloride, ethylbromoacetate, phenacylbromide and chloroacetone to give the corresponding benzimidazole derivatives 8-14.

Studies on formation of 1-aralkyl-2-aryl-6-benzoylbenzimidazoles from 4-benzoyl-o-phenylene diamine and aromatic aldehydes

Condensation of 4-benzyl-o-phenylenediamine (I) with aromatic aldehydes leads interestingly to 1-aralkyl-2-aryl-6- benzoylbenzimidazoles (III) besides the normal 2-aryl-5 (or 6)-benzoylbenzimidazoles (II). The intermediate has been shown to be not the dia