70176-71-5Relevant academic research and scientific papers
Iron(III) catalyzed direct C–H functionalization at the C-3 position of chromone for the synthesis of fused chromeno-quinoline scaffolds
Kumar, T. Uday,Roy, Durba,Bhattacharya, Anupam
, p. 1895 - 1898 (2019)
This communication describes an iron-catalyzed route for the synthesis of 6-substituted chromeno[3,2-c]quinolin-7-one. The method developed does not require any pre-functionalization to execute the pivotal coupling reaction at the C-3 position of flavones
Reductive coupling reactions of 2-nitrochalcones and their β-hydroxy-analogues: New syntheses of 2-arylquinoline and 2-aryl-4-hydroxyquinoline derivatives
Barros, Ana I.R.N.A.,Dias, Andre F. R.,Silva, Artur M. S.
, p. 585 - 594 (2008/02/03)
A one-pot synthesis of novel 2-arylquinolines and 2-aryl-4- hydroxyquinolines was developed from the intramolecular reductive coupling reactions of 2-nitrochalcones and 3-hydroxy-1-phenyl-3-(2-nitrophenyl)-2-propen- 1-ones. Depending on the reduction method and on the presence of electron donating substituents on the A ring of 2-nitrochalcones one can modulate the formation of 2-arylquinolines, their N-oxides, and of 2-aminochalcones. The reduction of 3-hydroxy-1-(2-hydroxyphenyl)-3-(2-nitrophenyl)-2-propen-1-ones with stannous chloride in hydrochloric acid gave 2′-aminoflavones and with ammonium formate and Pd/C yielded 2-(2-hydroxyaryl)-4-hydroxyquinolines. Springer-Verlag 2007.
Synthesis and structure elucidation of five series of aminoflavones using 1D and 2D NMR spectroscopy
Barros, Ana I. R. N. A.,Silva, Artur M. S.
, p. 1122 - 1127 (2008/02/03)
Twenty-six new aminoflavones have been synthesised by two different methods and the structure elucidation was accomplished using extensive 1D ( 1H, 13C) and 2D NMR spectroscopic studies (COSY, HSQC and HMBC experiments). Copyright
