701975-89-5

Basic information

• Product Name: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2-diphenyl-, O-methyloxime, (1Z)-
• CAS NO: 701975-89-5
• Molecular Formula: C21H29NO2Si
• Molecular Weight: 355.552
• Mol File: 701975-89-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2-diphenyl-, O-methyloxime, (1Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2-diphenyl-, O-methyloxime, (1Z)-(701975-89-5)
• EPA Substance Registry System: Ethanone, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2-diphenyl-, O-methyloxime, (1Z)-(701975-89-5)

Safety Data

• Hazardous Substances Data: 701975-89-5(Hazardous Substances Data)

Upstream product

• 185197-15-3 phenylmethyl (Z)-N-methoxybenzimidate 
• 185197-24-4 phenylmethyl (E)-N-methoxybenzimidate 
• 98-88-4 benzoyl chloride 
• 41071-35-6 (Z)-N-methoxybenzenecarboximidoyl chloride 
• 2446-51-7 N-methoxybenzamide 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 161869-75-6 (Z)-2-hydroxy-1,2-diphenylethanone O-methyloxime 

Downstream Products

• 530-36-9 threo-1,2-diphenyl-2-aminoethan-1-ol 
• 530-36-9 erythro-2-amino-1,2-diphenylethanol 

Relevant articles and documents

Imino 1,2-Wittig rearrangement of hydroximates and its application to synthesis of cytoxazone

The imino 1,2-Wittig rearrangement of hydroximates provides a novel method for the construction of 2-hydroxyoxime ethers. Upon treatment with LDA, Z-hydroximates smoothly underwent stereoselective rearrangement to give Z-2-hydroxyoxime ethers in good yield, which were converted into amino alcohols. On the other hand, the rearrangement of E-hydroximates gave a mixture of E- and Z-2-hydroxyoxime ethers. This method was successfully applied to a practical synthesis of cytoxazone.