70298-77-0

Basic information

• Product Name: 2,2-Diphenyl-4'-nitroacetanilide
• Synonyms: 2,2-Diphenyl-4'-nitroacetanilide
• CAS NO: 70298-77-0
• Molecular Formula: C₂₀H₁₆N₂O₃
• Molecular Weight: 332.3526
• Mol File: 70298-77-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 575.9°Cat760mmHg
• Flash Point: 302.1°C
• Appearance: /
• Density: 1.283g/cm³
• Vapor Pressure: 2.89E-13mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: 2,2-Diphenyl-4'-nitroacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Diphenyl-4'-nitroacetanilide(70298-77-0)
• EPA Substance Registry System: 2,2-Diphenyl-4'-nitroacetanilide(70298-77-0)

Safety Data

• Hazardous Substances Data: 70298-77-0(Hazardous Substances Data)

Usage

Chemical structure

4'-nitroacetanilide core with two phenyl groups attached at the 2 position

Analgesic properties

Pain-relieving

Antipyretic properties

Fever-reducing

Mechanism of action

Inhibits the production of prostaglandins in the brain

Typical uses

Alleviating mild to moderate pain (e.g., headaches, muscle aches, toothaches) and reducing fevers

Safety

Considered safe and effective when used as directed

Toxicity

Can be toxic in high doses or when combined with certain substances (e.g., alcohol)

InChI:InChI=1/C20H16N2O3/c23-20(21-17-11-13-18(14-12-17)22(24)25)19(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-14,19H,(H,21,23)

Upstream product

• 100-01-6 4-nitro-aniline 
• 3469-17-8 2-diazo-1,2-diphenylethan-1-one 
• 22731-52-8 N-(Diphenylethenylidene)-4-nitrobenzeneamine 
• 1871-76-7 diphenylacetic acid chloride 
• 117-34-0 2,2-diphenylacetic acid 
• 1516-60-5 4-nitrophenyl azide 
• 4107-01-1 N-(p-tolyl)diphenylacetamide 

Downstream Products

• 22731-52-8 N-(Diphenylethenylidene)-4-nitrobenzeneamine 
• 119-61-9 benzophenone 
• 117-34-0 2,2-diphenylacetic acid 
• 5267-35-6 N-(diphenylmethyl)acetamide 
• 22800-71-1 N-(diphenylmethylene)acetamide 
• 1375263-32-3 1-acetyl-3,3-diphenylaziridin-2-one 
• 100-01-6 4-nitro-aniline 
• 198337-87-0 C₂₀H₁₆FNO 
• 349644-59-3 C₂₁H₁₆N₂O 
• 4695-13-0 2,2-diphenylacetamide 
• 86-29-3 Diphenylacetonitrile 
• 70481-06-0 N-<4-Brom-phenyl>-diphenylacetamid 
• 24765-98-8 4-chlorophenyldiphenylacetamide 
• 152309-20-1 N-(4-Cyano-phenyl)-2,2-diphenyl-acetamide 

Relevant articles and documents

Reaction of azides and enolisable aldehydes under the catalysis of organic bases and: Cinchona based quaternary ammonium salts

Herein we report a two-step sequence for the preparation of amides starting from azides and enolisable aldehydes. The reaction proceeded via the formation of triazoline intermediates that were converted into amides via Lewis acid catalysis. Preliminary st

Electronic, steric and acid-base effects on the anodic oxidation of aryl-substituted ketene imines

Aryl-substituted ketene imines (1a-1i) have been studied both in dichloromethane and acetonitrile by cyclic voltammetry. In addition to the multi-annulated heterocycles products of type 2-4 previously obtained by ketene imines 1a-1d, the anodic oxidation of ketene imines containing electron-withdrawing substituents and electron-donating substituents at the ortho position, affords also monocyclic dimers of type 5 (from 1e-1f) and of type 6 (from 1h-1i). The results are discussed in terms of both electronic and steric effects.