198337-87-0

Basic information

• Product Name: N-(4-fluorophenyl)-2,2-diphenylacetamide
• Synonyms: N-(4-fluorophenyl)-2,2-diphenylacetamide;Benzeneacetamide, N-(4-fluorophenyl)-α-phenyl-
• CAS NO: 198337-87-0
• Molecular Formula: C₂₀H₁₆FNO
• Molecular Weight: 305.35
• Mol File: 198337-87-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-fluorophenyl)-2,2-diphenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-fluorophenyl)-2,2-diphenylacetamide(198337-87-0)
• EPA Substance Registry System: N-(4-fluorophenyl)-2,2-diphenylacetamide(198337-87-0)

Safety Data

• Hazardous Substances Data: 198337-87-0(Hazardous Substances Data)

Upstream product

• 70298-76-9 N-(3-Nitrophenyl)-diphenylacetamid 
• 70298-77-0 N-(4-nitrophenyl)-2,2-di-phenylacetamide 
• 4107-01-1 N-(p-tolyl)diphenylacetamide 
• 117-34-0 2,2-diphenylacetic acid 
• 371-40-4 4-fluoroaniline 
• 349644-59-3 C₂₁H₁₆N₂O 

Downstream Products

• 119-61-9 benzophenone 
• 4695-13-0 2,2-diphenylacetamide 
• 86-29-3 Diphenylacetonitrile 
• 5267-35-6 N-(diphenylmethyl)acetamide 
• 22800-71-1 N-(diphenylmethylene)acetamide 
• 1375263-32-3 1-acetyl-3,3-diphenylaziridin-2-one 
• 371-40-4 4-fluoroaniline 

Relevant articles and documents

Electrochemical oxidation of amides of type Ph2CHCONHAr

Anodic oxidation of N-aryl-2,2-diphenylacetamides in acetonitrile undergoes three types of bond-cleavage, one between the benzylic carbon and the carbonyl group, the second between a carbonyl and 'N', and the third between the 'N' atom and aryl group. The selectivity of the cleavage and nature of emerged products is highly dependent on the nature of substituent attached to the aryl group. For example, electron-withdrawing groups direct the benzyl-carbonyl bond-breaking whereas electron-donating substituents favor the N-aryl bond cleavage. The type of products obtained involve benzophenone, 2,2-diphenylacetamide, N-(diphenylmethylene)acetamide, N-(diphenylmethyl)acetamide, α-lactam (1-acetyl-3,3-diphenylaziridin-2-one, as a 1:1 complex with 2,4-dinitroaniline) and aniline derivatives.