5267-35-6

Basic information

• Product Name: Acetamide, N-(diphenylmethyl)-
• CAS NO: 5267-35-6
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 5267-35-6.mol
• Article Data: 72

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(diphenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(diphenylmethyl)-(5267-35-6)
• EPA Substance Registry System: Acetamide, N-(diphenylmethyl)-(5267-35-6)

Safety Data

• Hazardous Substances Data: 5267-35-6(Hazardous Substances Data)

Upstream product

• 10199-64-1 1-acetyl-1H-pyrazole 
• 91-00-9 Benzhydrylamine 
• 3531-43-9 tetraisobutyl stannane 
• 60-35-5 acetamide 
• 91-01-0 1,1-Diphenylmethanol 
• 509-14-8 tetranitromethane 
• 21122-20-3 benzhydryl(phenyl)sulfane 
• 90-99-3 diphenylchloromethane 
• 776-74-9 Bromodiphenylmethane 
• 198337-87-0 C₂₀H₁₆FNO 
• 349644-59-3 C₂₁H₁₆N₂O 
• 117-34-0 2,2-diphenylacetic acid 
• 4695-14-1 2,2-diphenylacetanilide 
• 4107-01-1 N-(p-tolyl)diphenylacetamide 

Downstream Products

• 53693-47-3 N-benzhydrylethanamine 
• 52433-25-7 N-(diphenylmethyl)ethanethioamide 
• 119-61-9 benzophenone 

Relevant articles and documents

Electrophile-induced nucleophilic substitution of the nido- dicarbaundecaborate anion nido-7,8-c2b9h12 by conjugated heterodienes

Substitution of the dicarbaundecaborate anion nido-7,8-C2B9H12 (1) by precise hydride abstraction followed by nucleophilic attack usually leads to symmetric products 10-R-nido-7,8-C2B9H11. However, thioacetamide (MeC(S)NH2) as nucleophile and acetone/AlCl3 as hydride abstractor gave asymmetric 9-[MeC(NHiPr)S]-nido-7,8-C2B9H11 (2), whereas N,N-dimethylthioacetamide (MeC(S)NMe2) gave the expected symmetric 10-[MeC(NMe2)S]-nido-7,8-C2B9H11 (4). For the formation of 2, acetone and thioacetamide are assumed to give the intermediate MeC(S)N(CMe2) (3), which then attacks 1 with formation of 2. Similarly, reaction of acetyliminium chloride [MeC(O)NH(CPh2)]Cl (5) with 1 in THF gave a mixture of 9-and 10-substituted [MeC(NHCHPh2)O]-nido-7,8-C2B9H11 (6 and 7, respectively). These reactions are the first examples in which compounds (here heterodienes) that unite the functionalities of both hydride acceptor and nucleophilic site react with 1 in a bimolecular fashion. Furthermore, the analogous reaction of 1 and 5 (in an equilibrium mixture with acetyl chloride and benzophenone imine) in MeCN afforded 10-[MeC(NCPh2)NH]-nido-7,8-C2B9H11 (8) and MeC(O)NHCHPh2 (9).

C-H Amination via Electrophotocatalytic Ritter-Type Reaction

A method for C-H bond amination via an electrophotocatalytic Ritter-Type reaction is described. The reaction is catalyzed by a trisaminocyclopropenium (TAC) ion in an electrochemical cell under irradiation. These conditions convert benzylic C-H bonds to acetamides without the use of a stoichiometric chemical oxidant. A range of functionality is shown to be compatible with this transformation, and several complex substrates are demonstrated.

New approach for induction of alkyl moiety to aliphatic amines by NaBH(OAc)3 with carboxylic acid

We had found the novel N-alkylation method, which utilizes carboxylic acids as alkyl sources with sodium triacetoxyborohydride [NaBH(OAc)3]. Our methodology had been revealed to have some advantages over the reported similar procedures. Through