4107-01-1

Basic information

• Product Name: 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE
• Synonyms: 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE;AURORA KA-3648;N-(4-methylphenyl)-2,2-diphenylacetamide
• CAS NO: 4107-01-1
• Molecular Formula: C₂₁H₁₉NO
• Molecular Weight: 301.38
• Mol File: 4107-01-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 509.3°C at 760 mmHg
• Flash Point: 309.7°C
• Appearance: /
• Density: 1.144g/cm³
• Vapor Pressure: 1.71E-10mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE(4107-01-1)
• EPA Substance Registry System: 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE(4107-01-1)

Safety Data

• Hazardous Substances Data: 4107-01-1(Hazardous Substances Data)

Usage

General Description

2,2-Diphenyl-N-p-tolyl-acetamide is a chemical compound that is commonly used as an intermediate in the synthesis of pharmaceuticals and dyes. It is an amide derivative of p-toluidine and is used in the production of various drugs and pharmaceuticals. This chemical is known for its analgesic and anti-inflammatory properties and is often used in the treatment of pain and fever. It is a white solid with a molecular weight of 291.37 g/mol and a melting point of 189-191°C. 2,2-Diphenyl-N-p-tolyl-acetamide is considered to be a potentially hazardous chemical and should be handled with caution and proper safety measures.

InChI:InChI=1/C21H19NO/c1-16-12-14-19(15-13-16)22-21(23)20(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-15,20H,1H3,(H,22,23)

Upstream product

• 5110-45-2 diphenylketene-N-p-tolylimine 
• 60-29-7 diethyl ether 
• 106-49-0 p-toluidine 
• 525-06-4 diphenyl ketene 
• 64-17-5 ethanol 
• 5110-46-3 2-chloro-2,2-diphenyl-N-p-tolyl-acetimidoyl chloride 
• 64-19-7 acetic acid 
• 79-11-8 chloroacetic acid 
• 104-94-9 4-methoxy-aniline 
• 62-53-3 aniline 
• 75-98-9 Trimethylacetic acid 
• 117-34-0 2,2-diphenylacetic acid 
• 32177-09-6 chloro-diphenyl-acetic acid p-toluidide 
• 91374-52-6 1-(2,2-diphenyl-1-chlorovinyl)-1-p-tolyl-2,2-dimethylurea 

Downstream Products

• 26907-03-9 2-benzhydrylidene-5-methyl-3-p-tolyl-[1,3]oxazinane-4,6-dione 
• 91374-51-5 N-(2,2-diphenyl-1-chlorovinyl)-N-(dimethylaminodichloromethyl)-p-toluidine 
• 5110-45-2 diphenylketene-N-p-tolylimine 
• 18351-81-0 di-tert-butyl-methylphosphine oxide 
• 76711-24-5 C₉H₂₁Cl₂P 
• 119-61-9 benzophenone 
• 4695-13-0 2,2-diphenylacetamide 
• 117-34-0 2,2-diphenylacetic acid 
• 86-29-3 Diphenylacetonitrile 
• 5267-35-6 N-(diphenylmethyl)acetamide 
• 22800-71-1 N-(diphenylmethylene)acetamide 
• 1375263-32-3 1-acetyl-3,3-diphenylaziridin-2-one 
• 198337-87-0 C₂₀H₁₆FNO 
• 70481-06-0 N-<4-Brom-phenyl>-diphenylacetamid 

Relevant articles and documents

Electrochemical oxidation of amides of type Ph2CHCONHAr

Anodic oxidation of N-aryl-2,2-diphenylacetamides in acetonitrile undergoes three types of bond-cleavage, one between the benzylic carbon and the carbonyl group, the second between a carbonyl and 'N', and the third between the 'N' atom and aryl group. The selectivity of the cleavage and nature of emerged products is highly dependent on the nature of substituent attached to the aryl group. For example, electron-withdrawing groups direct the benzyl-carbonyl bond-breaking whereas electron-donating substituents favor the N-aryl bond cleavage. The type of products obtained involve benzophenone, 2,2-diphenylacetamide, N-(diphenylmethylene)acetamide, N-(diphenylmethyl)acetamide, α-lactam (1-acetyl-3,3-diphenylaziridin-2-one, as a 1:1 complex with 2,4-dinitroaniline) and aniline derivatives.

Intermolecular Cyclization Processes in the Anodic Oxidation of Ketene Imines: Formation of Heterocyclic Dimers and Trimers

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ADDITION AT THE C=N BOND IN KETENE IMINES. REACTION OF DIPHENYLKETENE N-(p-TOLYL)IMINE WITH N,N-DIMETHYLDICHLOROMETHYLENEAMMONIUM CHLORIDE

Electrophilic addition to arylketene imines at the C=N bond is described for the reaction of diphenylketene N-(p-tolyl)imine with N,N-dimethyldichloromethyleneammonium chloride.Chlorinating characteristics were found in the complex of N,N-dimethyldichloromethyleneammonium chloride with chlorine.