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703-91-3

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703-91-3 Usage

General Description

5-Bromo-2-(trifluoromethyl)aniline is a chemical compound with the molecular formula C7H5BrF3N. It is a white to off-white crystalline powder that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 5-Bromo-2-(trifluoromethyl)aniline is also a valuable building block in organic chemistry and is used in the production of dyes, pigments, and other specialty chemicals. 5-Bromo-2-(trifluoromethyl)aniline is a versatile reagent with a wide range of applications in the chemical and pharmaceutical industries, making it an important compound for various synthetic processes. Due to its potential use in many different fields, its properties and uses continue to be studied and expanded.

Check Digit Verification of cas no

The CAS Registry Mumber 703-91-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 703-91:
(5*7)+(4*0)+(3*3)+(2*9)+(1*1)=63
63 % 10 = 3
So 703-91-3 is a valid CAS Registry Number.

703-91-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-2-(Trifluoromethyl)Aniline

1.2 Other means of identification

Product number -
Other names 5-Bromo-2-(trifluoromethyl)aniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:703-91-3 SDS

703-91-3Relevant articles and documents

Coordinating Activation Strategy-Induced Selective C?H Trifluoromethylation of Anilines

Xu, Jun,Cheng, Ke,Shen, Chao,Bai, Renren,Xie, Yuanyuan,Zhang, Pengfei

, p. 965 - 970 (2018/02/12)

A simple protocol for the synthesis of 2-(trifluoromethyl)aniline derivatives through a coordinating activation strategy was developed. The reaction showed good reactivity and gave the target products in moderate to good yields. Pleasingly, the directing group could be recovered in excellent yield. Furthermore, this strategy allowed efficient access to the synthesis of floctafenine. A single-electron-transfer mechanism was proposed to be responsible for this trifluoromethylation reaction.

Preparation method of trifluoromethylamine

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Paragraph 0212-0216; 0220-0222; 0226-0228, (2018/09/28)

The invention relates to a preparation method of trifluoromethylamine. The method includes the following steps that aromatic amine shown in the formula (1) and a trifluoromethyl reagent shown in the formula (2) react in a solvent under the condition that an alkali and/or nickel compound exists, and the trifluoromethylamine compound shown in the formula (3) is generated. According to the preparation method of trifluoromethylamine, aromatic amine and 1-trifluoromethyl-1,2-iodobenzoyl-3(H)-ketone serve as raw materials and react under the condition that the alkali and/or nickel compound exists through the amino positioning effect on aromatic nucleus. The synthesis steps of the method are simple, the cost of the raw materials is low, the production cost of trifluoromethylamine can be greatly reduced, and large-scale industrialized production is promoted.

MK2 INHIBITORS AND USES THEREOF

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Paragraph 00763; 00895, (2014/10/03)

The present invention provides compounds, compositions thereof, and methods of using the same.

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