705264-93-3

Basic information

• Product Name: 1H-Indazole-3-Methanol, 5-broMo-
• Synonyms: 1H-Indazole-3-Methanol, 5-broMo-;(5-Bromo-1H-indazol-3-yl)methanol
• CAS NO: 705264-93-3
• Molecular Formula: C₈H₇BrN₂O
• Molecular Weight: 227.05798
• EINECS: 230-905-8
• Mol File: 705264-93-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indazole-3-Methanol, 5-broMo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indazole-3-Methanol, 5-broMo-(705264-93-3)
• EPA Substance Registry System: 1H-Indazole-3-Methanol, 5-broMo-(705264-93-3)

Safety Data

• Hazardous Substances Data: 705264-93-3(Hazardous Substances Data)

Usage

General Description

1H-Indazole-3-methanol, 5-bromo- is a chemical compound with the molecular formula C8H7BrN2O. It is a derivative of indazole, a heterocyclic organic compound with a bicyclic structure containing both nitrogen and carbon atoms. The addition of a bromine atom to the 5th position of the indazole ring gives this compound unique properties and potential applications in various fields. It may be used in the synthesis of pharmaceuticals, agrochemicals, or other specialty chemicals due to its versatile reactivity and potential biological activities. Furthermore, its structure and properties make it a valuable building block for designing and creating new compounds for research and development purposes.

Upstream product

• 1077-94-7 5-bromobenzopyrazole-3-carboxylic acid 
• 87-48-9 5-Bromo-1H-indole-2,3-dione 
• 78155-74-5 5-bromo-1H-indazole-3-carboxylic acid methyl ester 
• 201227-38-5 5-bromo-1H-indazole-3-carboxaldehyde 
• 1081-04-5 5-bromo-1H-indazole-3-carboxylic acid ethyl ester 

Downstream Products

• 705264-94-4 (5-bromo-1H-indazol-3-ylmethyl)triphenylphosphonium bromide 

Relevant articles and documents

ANTICANCER AGENT

An anticancer agent comprising a compound represented by the formula (I) [R1 represents hydrogen atom, hydroxyl group, a C1-6alkoxy group and the like; R2 and R3 represents hydrogen atom, a halogen atom, a C1-6alkyl group and the like; R4 represents hydrogen atom, a C1-6alkyl group, a C1-6alkylsulfonyl group and the like; R5 represents hydrogen atom or a substituent; .... represents a single bond or a double bond; R6 and R7 represents hydrogen atom, a C1-6alkyl group and the like; R8 represents hydrogen atom, a C1-6alkyl group and the like; A represents -O-, -S-, or - CH2-; D represents -C= or -N=; X represents methylene group, -O-, or -CO-; Q represents -N= or -C(R8)=; and Y represents a heterocyclic group or amino group], which shows a superior inhibitory activity against pim-1 kinase.

JNK INHIBITOR

The present invention provides a JNK inhibitor comprising, as an active ingredient, an indazole derivative represented by Formula (I) [wherein R1 represents substituted or unsubstituted aryl or the like and R2 represents a hydrogen a