70724-72-0

Usage

Uses

Used in Pharmaceutical Industry:
N-PIPERIDIN-4-YLMETHANESULFONAMIDE is used as a potential antihypertensive and vasodilator agent for its ability to lower blood pressure and improve blood flow.
Used in Neurodegenerative Disease Treatment:
N-PIPERIDIN-4-YLMETHANESULFONAMIDE is used as a potential therapeutic agent for the treatment of neurodegenerative diseases, due to its potential neuroprotective and disease-modifying properties.
Used in Chemical Synthesis:
N-PIPERIDIN-4-YLMETHANESULFONAMIDE is used as a building block in the synthesis of other compounds with pharmaceutical and biological relevance, contributing to the development of new drugs and therapeutic agents.
Further research is ongoing to explore the full range of potential applications for N-PIPERIDIN-4-YLMETHANOLSULFONAMIDE, as its pharmacological properties and potential uses continue to be investigated.

InChI:InChI=1/C6H14N2O2S/c1-11(9,10)8-6-2-4-7-5-3-6/h6-8H,2-5H2,1H3

Upstream product

• 68996-25-8 N-(1-Benzylpiperidin-4-yl)methanesulfonamide 
• 50541-93-0 4-amino-1-benzylpiperidine 
• 124-63-0 methanesulfonyl chloride 
• 87120-72-7 1-(tert-butoxycarbonyl)-4-aminopiperidine 
• 800401-97-2 tert-butyl 4-(methylsulfonamido)piperidine-1-carboxylate 
• 50893-53-3 carbonochloridic acid 1-chloro-ethyl ester 

Downstream Products

• 1131739-21-3 2-(3,4-dichloro-phenyl)-4-(4-methanesulfonylamino-piperidin-1-yl)-butyric acid methyl ester 
• 1131739-16-6 2-(3,4-dichloro-phenyl)-4-(4-methanesulfonylamino-piperidin-1-yl)-2-methyl-butyric acid methyl ester 
• 1206772-14-6 N-[1-[2-[3-tert-butyl-2-methoxy-5-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]-4-piperidyl]methanesulfonamide 
• 1359969-52-0 2-chloro-4-(3-cyclopentyl-7-(4-(methylsulfonyl)piperazine-1-carbonyl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinolin-2-yl)benzonitrile 
• 1359969-49-5 N-(1-(2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinoline-7-carbonyl)piperidin-4-yl)methanesulfonamide 
• 1445902-03-3 N-isobutyl-N-[4-(4-(methylsulfonamido)piperidin-1-yl)benzyl]-1-phenylmethanesulfonamide 
• 1424393-63-4 N-(1-(4-nitrophenyl)piperidin-4-yl)methanesulfonamide 

Relevant academic research and scientific papers

Fused Ring Compound For Use As Mineralocorticoid Receptor Antagonist

The present invention belongs to the technical field of medicine, relating in particular to: a fused ring compound as represented by Formula (I) for use as a mineralocorticoid receptor antagonist, a pharmaceutically acceptable salt thereof, and an isomer thereof; a preparation method for these compounds; a pharmaceutical preparation containing these compounds; and an application of these compounds, the pharmaceutically acceptable salt thereof, or the isomers thereof in the preparation of medicants for the treatment and/or prevention of kidney injury, cardiovascular diseases such as hypertension, and/or endocrine disease. The definitions of X, Y1, Y2, Y3, R1, R2a, R2b, R3a, R3b, R4, Cy and n are as presented in the description.

FUSED RING COMPOUND FOR USE AS MINERALOCORTICOID RECEPTOR ANTAGONIST

The present invention belongs to the technical field of medicine, relating in particular to: a fused ring compound as represented by Formula (I) for use as a mineralocorticoid receptor antagonist, a pharmaceutically acceptable salt thereof, and an isomer thereof; a preparation method for these compounds; a pharmaceutical preparation containing these compounds; and an application of these compounds, the pharmaceutically acceptable salt thereof, or the isomers thereof in the preparation of medicants for the treatment and/or prevention of kidney injury, cardiovascular diseases such as hypertension, and/or endocrine disease. The definitions of X, Y1, Y2, Y3, R1, R2a,R2b , R3a , R3b, R4, Cy and n are as presented in the description.

Rifamycin analogs and uses thereof

The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3′-hydroxy analogs, 4′-and/or 6′ halo and/or alkoxy analogs, and various 5′ substituents that incorporate a cyclic amine moiety.

Rifamycin analogs and uses thereof

The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3′-hydroxy analogs, 4′- and/or 6′ halo and/or alkoxy analogs, and various 5′ substituents that incorporate a cyclic amine moiety.

PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.

1-PIPERIDINOPHTHALAZINES AS CARDIAC STIMULANTS

A series of 1-piperidinophthalazine derivatives as phosphodiesterase inhibitors and cardiac stimulants