40751-52-8

Basic information

• Product Name: Benzonitrile, 2-(1-methylethyl)-
• Synonyms: 2-Isopropyl-1-benzonitrile;2-(i-Pr)-C6H4CN;Benzonitrile,2-(1-methylethyl);2-Isopropyl-benzonitrile;2-Isopropyl-benzonitril
• CAS NO: 40751-52-8
• Molecular Formula: C10H11N
• Molecular Weight: 145.204
• Mol File: 40751-52-8.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 105-107 °C(Press: 16 Torr)
• Density: 0.96±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzonitrile, 2-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 2-(1-methylethyl)-(40751-52-8)
• EPA Substance Registry System: Benzonitrile, 2-(1-methylethyl)-(40751-52-8)

Safety Data

• Hazardous Substances Data: 40751-52-8(Hazardous Substances Data)

Upstream product

• 544-92-3 copper(I) cyanide 
• 643-28-7 2-isopropylaniline 
• 7073-94-1 1-bromo-2-isopropylbenzene 
• 98-82-8 Isopropylbenzene 
• 19099-54-8 2-isopropyliodobenzene 
• 13435-20-6 tetraethylammoniumcyanide 
• 591-87-7 Allyl acetate 
• 2042-37-7 o-cyanobromobenzene 
• 1068-55-9 isopropylmagnesium chloride 
• 75-05-8 acetonitrile 
• 75-30-9 2-iodo-propane 
• 611-20-1 salicylonitrile 
• 77047-87-1 isopropyl zinc bromide 
• 873-32-5 2-Chlorobenzonitrile 

Downstream Products

• 129976-25-6 1-(2-Isopropyl-phenyl)-2-methyl-2-phenyl-propan-1-one 
• 6623-98-9 2-Isopropylbenzoesaeuremethylester 
• 2438-04-2 2-isopropylbenzoic acid 
• 129976-23-4 1-o-cumyl-3-phenyl-1-butanone 
• 71254-87-0 1-(2-Isopropyl-phenyl)-2-phenyl-propan-1-one 
• 56177-33-4 2-isopropylbenzamide 
• 19103-09-4 (2-isopropylphenyl)(phenyl)methanone 

Relevant articles and documents

SUBSTITUTED HETEROCYCLIC AMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF

Provided are a substituted heterocyclic amide compound having a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the

Visible-Light-Mediated Aromatic Substitution Reactions of Cyanoarenes with 4-Alkyl-1,4-dihydropyridines through Double Carbon-Carbon Bond Cleavage

Novel aromatic substitution reactions of cyanoarenes with 4-alkyl-1,4-dihydropyridines as alkylating reagents in the presence of a catalytic amount of a photoredox catalyst proceed smoothly to give the corresponding alkyl-substituted arenes in good to high yields. The present reaction system realizes a novel C-C bond-forming reaction between two fragments generated from the C-C bond-cleavage reactions of two independent substrates.

Acetonitrile as a cyanating reagent: Cu-catalyzed cyanation of arenes

A novel approach to the Cu-catalyzed cyanation of simple arenes using acetonitrile as an attractive cyano source has been documented. The C-H functionalization of arenes without directing groups involves a sequential iodination/cyanation to give the desired aromatic nitriles in good yields. A highly efficient Cu/TEMPO system for acetonitrile C-CN bond cleavage has been discovered. TEMPO is used as a cheap oxidant and enables the reaction to be catalytic in copper. Moreover, TEMPOCH2CN 6 has been identified as the active cyanating agent and shows high reactivity for forming the -CN moiety.