70738-48-6Relevant articles and documents
An enantioselective approach to the preparation of chiral sulfones by ir-catalyzed asymmetric hydrogenation
Peters, Byron K.,Zhou, Taigang,Rujirawanich, Janjira,Cadu, Alban,Singh, Thishana,Rabten, Wangchuk,Kerdphon, Sutthichat,Andersson, Pher G.
supporting information, p. 16557 - 16562 (2015/01/09)
Several chiral sulfonyl compounds were prepared using the iridium catalyzed asymmetric hydrogenation reaction. Vinylic, allylic and homoallylic sulfone substitutions were investigated, and high enantioselectivity is maintained regardless of the location of the olefin with respect to the sulfone. Impressive stereoselectivity was obtained for dialkyl substitutions, which typically are challenging substrates in the hydrogenation. As expected, the more bulky Z-substrates were hydrogenated slower than the corresponding E isomers, and in slightly lower enantioselectivity.
HETEROCONJUGATE ADDITION OF LITHIUM ALKYLS TO SUBSTITUTED HETERO-OLEFINS CONJUGATED WITH SULFUR AND SILICON ATOMS
Isobe, Minoru,Kitamura, Masato,Goto, Toshio
, p. 331 - 334 (2007/10/02)
Lithium alkyls and a lithiated sulfone carbanion readily added to the substituted hetero-olefins conjugated with silicon and sulfone-sulfur atoms among other combination of the third (or fourth) row hetero atoms, e.g.Si, Se and S.
