70817-26-4

Basic information

• Product Name: (1-Phenyl-1H-pyrazol-4-yl)methanol
• Synonyms: 1H-pyrazole-4-methanol, 1-phenyl-;(1-Phenyl-1H-pyrazol-4-yl)methanol;(1-phenyl-1H-pyrazol-4-yl)methanol(SALTDATA: FREE);(1-phenyl-4-pyrazolyl)methanol;(1-phenylpyrazol-4-yl)methanol;AG-613/31140002;ZINC00340724
• CAS NO: 70817-26-4
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.2
• Mol File: 70817-26-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 110-111 °C(Solv: water (7732-18-5))
• Boiling Point: 332.3 °C at 760 mmHg
• Flash Point: 154.8 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 5.86E-05mmHg at 25°C
• Refractive Index: 1.604
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.01±0.10(Predicted)
• CAS DataBase Reference: (1-Phenyl-1H-pyrazol-4-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1-Phenyl-1H-pyrazol-4-yl)methanol(70817-26-4)
• EPA Substance Registry System: (1-Phenyl-1H-pyrazol-4-yl)methanol(70817-26-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 70817-26-4(Hazardous Substances Data)

Usage

General Description

(1-Phenyl-1H-pyrazol-4-yl)methanol, also known as 4-Hydroxy-1-[3-(phenyl)pyrazol-1-yl]benzene, is a chemical compound with the formula C13H11N3O. It is a white to off-white crystalline powder that is insoluble in water but soluble in organic solvents. (1-Phenyl-1H-pyrazol-4-yl)methanol is commonly used in the pharmaceutical and chemical industries as an intermediate for the synthesis of various bioactive compounds, including pharmaceutical drugs. It is also known to exhibit biological activities, such as anti-inflammatory and analgesic properties, making it a potential candidate for drug development. Additionally, (1-Phenyl-1H-pyrazol-4-yl)methanol is widely utilized in organic synthesis and chemical research due to its versatile reactivity and functional groups.

InChI:InChI=1/C10H10N2O/c13-8-9-6-11-12(7-9)10-4-2-1-3-5-10/h1-7,13H,8H2

Upstream product

• 59-88-1 phenylhydrazine hydrochloride 
• 591-50-4 iodobenzene 
• 7188-96-7 1-Phenylpyrazol-4-carbonsaeure-methylester 
• 107-19-7 propargyl alcohol 
• 508191-77-3 3-phenylsydnone 
• 100-63-0 phenylhydrazine 
• 1126-00-7 1-phenylpyrazole 
• 885-94-9 ethyl 1-phenylpyrazole-4-carboxylate 
• 1134-50-5 4-carboxy-1-phenylpyrazole 
• 54605-72-0 1-phenyl-1H-pyrazole-4-carbaldehyde 

Downstream Products

• 54605-72-0 1-phenyl-1H-pyrazole-4-carbaldehyde 
• 1195983-13-1 (R)-1-(1-phenyl-1H-pyrazol-4-ylmethyl)-3-(1-thiophen-2-ylcycloheptanecarbonyloxy)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195983-01-7 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(1-phenyl-1H-pyrazol-4-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 35715-71-0 1-phenyl-4-pyrazolylmethyl chloride 
• 35715-77-6 (1-phenyl-1H-pyrazol-4-yl)-acetic acid 
• 51412-23-8 (1-phenyl-1H-pyrazol-4-yl)-acetonitrile 
• 101893-32-7 1,1'-phenyl-4,4'-dipyrazolylmethane 

Relevant articles and documents

NOVEL COMPOUND AS MTOR INHIBITOR AND USE THEREOF

The present invention relates to a novel compound as an mTOR inhibitor and a use thereof and, more specifically, to a novel compound represented by formula 1 that exhibits mTOR inhibitory activity and a pharmaceutical composition comprising same as an act

Solvent-free and montmorillonite K10-catalyzed domino reactions for the synthesis of pyrazoles with alkynylester as a dual synthon

A highly regioselective, solvent-free and montmorillonite K10 clay-catalyzed domino process with an unprecedented ring-closing C-C bond-formation reaction is described for the synthesis of a new class of 1,3,4-trisubstituted and 1,4-disubstituted pyrazole

Cu-catalysed pyrazole synthesis in continuous flow

The synthesis of 1,4-disubstituted pyrazoles via the cycloaddition reaction of sydnones and terminal alkynes has been achieved employing silica-supported copper catalysts. Furthermore, this methodology has been successfully implemented in continuous flow